Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception

ObjectivesThe ability to understand speech is highly variable in people with cochlear implants (CIs) and to date, there are no objective measures that identify the root of this discrepancy. However, behavioral measures of temporal processing such as the temporal modulation transfer function (TMTF) h...

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Main Authors: Ji-Hye Han, Andrew Dimitrijevic
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Neuroscience
Subjects:
N1
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00124/full
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spelling doaj-a815a4a96520445993d65d0f0ca694312020-11-25T02:11:45ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2020-02-011410.3389/fnins.2020.00124489214Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech PerceptionJi-Hye Han0Ji-Hye Han1Andrew Dimitrijevic2Andrew Dimitrijevic3Communication Sciences Research Center, Cincinnati Childs Hospital Medical Center, Cincinnati, OH, United StatesLaboratory of Brain & Cognitive Sciences for Convergence Medicine, College of Medicine, Hallym University, Chuncheon, South KoreaCommunication Sciences Research Center, Cincinnati Childs Hospital Medical Center, Cincinnati, OH, United StatesDepartment Otolaryngology-Head and Neck Surgery, Sunnybrook Health Sciences Centre, Faculty of Medicine, University of Toronto, Toronto, ON, CanadaObjectivesThe ability to understand speech is highly variable in people with cochlear implants (CIs) and to date, there are no objective measures that identify the root of this discrepancy. However, behavioral measures of temporal processing such as the temporal modulation transfer function (TMTF) has previously found to be related to vowel and consonant identification in CI users. The acoustic change complex (ACC) is a cortical auditory-evoked potential response that can be elicited by a “change” in an ongoing stimulus. In this study, the ACC elicited by amplitude modulation (AM) change was related to measures of speech perception as well as the amplitude detection threshold in CI users.MethodsTen CI users (mean age: 50 years old) participated in this study. All subjects participated in behavioral tests that included both speech and amplitude modulation detection to obtain a TMTF. CI users were categorized as “good” (n = 6) or “poor” (n = 4) based on their speech-in noise score (<50%). 64-channel electroencephalographic recordings were conducted while CI users passively listened to AM change sounds that were presented in a free field setting. The AM change stimulus was white noise with four different AM rates (4, 40, 100, and 300 Hz).ResultsBehavioral results show that AM detection thresholds in CI users were higher compared to the normal-hearing (NH) group for all AM rates. The electrophysiological data suggest that N1 responses were significantly decreased in amplitude and their latencies were increased in CI users compared to NH controls. In addition, the N1 latencies for the poor CI performers were delayed compared to the good CI performers. The N1 latency for 40 Hz AM was correlated with various speech perception measures.ConclusionOur data suggest that the ACC to AM change provides an objective index of speech perception abilities that can be used to explain some of the variation in speech perception observed among CI users.https://www.frontiersin.org/article/10.3389/fnins.2020.00124/fullacoustic change complexamplitude modulationtemporal modulation transfer functioncochlear implantsN1
collection DOAJ
language English
format Article
sources DOAJ
author Ji-Hye Han
Ji-Hye Han
Andrew Dimitrijevic
Andrew Dimitrijevic
spellingShingle Ji-Hye Han
Ji-Hye Han
Andrew Dimitrijevic
Andrew Dimitrijevic
Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception
Frontiers in Neuroscience
acoustic change complex
amplitude modulation
temporal modulation transfer function
cochlear implants
N1
author_facet Ji-Hye Han
Ji-Hye Han
Andrew Dimitrijevic
Andrew Dimitrijevic
author_sort Ji-Hye Han
title Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception
title_short Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception
title_full Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception
title_fullStr Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception
title_full_unstemmed Acoustic Change Responses to Amplitude Modulation in Cochlear Implant Users: Relationships to Speech Perception
title_sort acoustic change responses to amplitude modulation in cochlear implant users: relationships to speech perception
publisher Frontiers Media S.A.
series Frontiers in Neuroscience
issn 1662-453X
publishDate 2020-02-01
description ObjectivesThe ability to understand speech is highly variable in people with cochlear implants (CIs) and to date, there are no objective measures that identify the root of this discrepancy. However, behavioral measures of temporal processing such as the temporal modulation transfer function (TMTF) has previously found to be related to vowel and consonant identification in CI users. The acoustic change complex (ACC) is a cortical auditory-evoked potential response that can be elicited by a “change” in an ongoing stimulus. In this study, the ACC elicited by amplitude modulation (AM) change was related to measures of speech perception as well as the amplitude detection threshold in CI users.MethodsTen CI users (mean age: 50 years old) participated in this study. All subjects participated in behavioral tests that included both speech and amplitude modulation detection to obtain a TMTF. CI users were categorized as “good” (n = 6) or “poor” (n = 4) based on their speech-in noise score (<50%). 64-channel electroencephalographic recordings were conducted while CI users passively listened to AM change sounds that were presented in a free field setting. The AM change stimulus was white noise with four different AM rates (4, 40, 100, and 300 Hz).ResultsBehavioral results show that AM detection thresholds in CI users were higher compared to the normal-hearing (NH) group for all AM rates. The electrophysiological data suggest that N1 responses were significantly decreased in amplitude and their latencies were increased in CI users compared to NH controls. In addition, the N1 latencies for the poor CI performers were delayed compared to the good CI performers. The N1 latency for 40 Hz AM was correlated with various speech perception measures.ConclusionOur data suggest that the ACC to AM change provides an objective index of speech perception abilities that can be used to explain some of the variation in speech perception observed among CI users.
topic acoustic change complex
amplitude modulation
temporal modulation transfer function
cochlear implants
N1
url https://www.frontiersin.org/article/10.3389/fnins.2020.00124/full
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