Dielectrophoresis for Bioparticle Manipulation
As an ideal method to manipulate biological particles, the dielectrophoresis (DEP) technique has been widely used in clinical diagnosis, disease treatment, drug development, immunoassays, cell sorting, etc. This review summarizes the research in the field of bioparticle manipulation based on DEP tec...
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doaj-a822497aaebc46dd84a9ed6f49d033482020-11-24T23:18:55ZengMDPI AGInternational Journal of Molecular Sciences1422-00672014-10-011510182811830910.3390/ijms151018281ijms151018281Dielectrophoresis for Bioparticle ManipulationCheng Qian0Haibo Huang1Liguo Chen2Xiangpeng Li3Zunbiao Ge4Tao Chen5Zhan Yang6Lining Sun7Robotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaRobotics and Microsystems Center, College of Mechanical and Electrical Engineering & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215000, ChinaAs an ideal method to manipulate biological particles, the dielectrophoresis (DEP) technique has been widely used in clinical diagnosis, disease treatment, drug development, immunoassays, cell sorting, etc. This review summarizes the research in the field of bioparticle manipulation based on DEP techniques. Firstly, the basic principle of DEP and its classical theories are introduced in brief; Secondly, a detailed introduction on the DEP technique used for bioparticle manipulation is presented, in which the applications are classified into five fields: capturing bioparticles to specific regions, focusing bioparticles in the sample, characterizing biomolecular interaction and detecting microorganism, pairing cells for electrofusion and separating different kinds of bioparticles; Thirdly, the effect of DEP on bioparticle viability is analyzed; Finally, the DEP techniques are summarized and future trends in bioparticle manipulation are suggested.http://www.mdpi.com/1422-0067/15/10/18281dielectrophoresislab-on-a-chipbioparticletrappingdetectionfocusingpairingseparation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Cheng Qian Haibo Huang Liguo Chen Xiangpeng Li Zunbiao Ge Tao Chen Zhan Yang Lining Sun |
spellingShingle |
Cheng Qian Haibo Huang Liguo Chen Xiangpeng Li Zunbiao Ge Tao Chen Zhan Yang Lining Sun Dielectrophoresis for Bioparticle Manipulation International Journal of Molecular Sciences dielectrophoresis lab-on-a-chip bioparticle trapping detection focusing pairing separation |
author_facet |
Cheng Qian Haibo Huang Liguo Chen Xiangpeng Li Zunbiao Ge Tao Chen Zhan Yang Lining Sun |
author_sort |
Cheng Qian |
title |
Dielectrophoresis for Bioparticle Manipulation |
title_short |
Dielectrophoresis for Bioparticle Manipulation |
title_full |
Dielectrophoresis for Bioparticle Manipulation |
title_fullStr |
Dielectrophoresis for Bioparticle Manipulation |
title_full_unstemmed |
Dielectrophoresis for Bioparticle Manipulation |
title_sort |
dielectrophoresis for bioparticle manipulation |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1422-0067 |
publishDate |
2014-10-01 |
description |
As an ideal method to manipulate biological particles, the dielectrophoresis (DEP) technique has been widely used in clinical diagnosis, disease treatment, drug development, immunoassays, cell sorting, etc. This review summarizes the research in the field of bioparticle manipulation based on DEP techniques. Firstly, the basic principle of DEP and its classical theories are introduced in brief; Secondly, a detailed introduction on the DEP technique used for bioparticle manipulation is presented, in which the applications are classified into five fields: capturing bioparticles to specific regions, focusing bioparticles in the sample, characterizing biomolecular interaction and detecting microorganism, pairing cells for electrofusion and separating different kinds of bioparticles; Thirdly, the effect of DEP on bioparticle viability is analyzed; Finally, the DEP techniques are summarized and future trends in bioparticle manipulation are suggested. |
topic |
dielectrophoresis lab-on-a-chip bioparticle trapping detection focusing pairing separation |
url |
http://www.mdpi.com/1422-0067/15/10/18281 |
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