Expression ratio of CCND1 to CDKN2A mRNA predicts RB1 status of cultured cancer cell lines and clinical tumor samples

<p>Abstract</p> <p>Background</p> <p>The retinoblastoma product (RB1) is frequently deregulated in various types of tumors by mutation, deletion, or inactivation through association with viral oncoproteins. The functional loss of RB1 is recognized to be one of the hallm...

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Bibliographic Details
Main Authors: Itadani Hiraku, Komatani Hideya, Kobayashi Tsutomu, Machida Takumitsu, Mizuarai Shinji, Kotani Hidehito
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/31

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