Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

<p>Abstract</p> <p>Background</p> <p>Brain-Derived Neurotrophic Factor (BDNF) is the main candidate for neuroprotective therapy for Huntington's disease (HD), but its conditional administration is one of its most challenging problems.</p> <p>Results<...

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Bibliographic Details
Main Authors: Lao-Peregrin Cristina, Carretón Olga, Giralt Albert, Martín Eduardo D, Alberch Jordi
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Molecular Neurodegeneration
Subjects:
Huntingtin
synaptic plasticity
therapy
astrocytes
learning
Long-term potentiation
Online Access:http://www.molecularneurodegeneration.com/content/6/1/71

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