Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

Summary: In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri-implantation window of human development. H...

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Bibliographic Details
Main Authors:	Di Chen, Na Sun, Lei Hou, Rachel Kim, Jared Faith, Marianna Aslanyan, Yu Tao, Yi Zheng, Jianping Fu, Wanlu Liu, Manolis Kellis, Amander Clark
Format:	Article
Language:	English
Published:	Elsevier 2019-12-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124719315748

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