Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future
Background: Diabetes mellitus (DM) is a major global public health problem. Lack of adherence to medication causes suboptimal glycemic control increasing complication rates, costs and mortality. The objective of the study was to determine current antidiabetic medication adherence in Botswana and ass...
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doaj-a8c16f63787746e68ceba6fa97f1a1dc2021-01-02T09:22:00ZengTaylor & Francis GroupAlexandria Journal of Medicine2090-50682018-06-01542103109Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the futureGodfrey Mutashambara Rwegerera0Thato Moshomo1Marea Gaenamong2Taibat Aderonke Oyewo3Sivasomnath Gollakota4Francis Apolinary Mhimbira5Joseph Fadare6Brian Godman7Johanna C. Meyer8Yordanka Piña Rivera9Faculty of Medicine, Department of Internal Medicine, University of Botswana and Department of Medicine, Princess Marina Hospital, Gaborone, Botswana; Corresponding author at: Godfrey Mutashambara Rwegerera, Department of Internal Medicine, Faculty of Medicine, University of Botswana, Botswana.Department of Medicine, Princess Marina Hospital, Gaborone, BotswanaDepartment of Accident and Emergency, Princess Marina Hospital, Gaborone, BotswanaDepartment of Medicine, Princess Marina Hospital, Gaborone, BotswanaDepartment of Medicine, Princess Marina Hospital, Gaborone, BotswanaIfakara Health Institute, Morogoro, TanzaniaDepartment of Pharmacology and Therapeutics College of Medicine, Ekiti State University, Ado-Ekiti, NigeriaDepartment of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United KingdomDepartment of Pharmacy, Faculty of Health Sciences, School of Health Care Sciences, Sefako Makgatho Health Sciences University, South AfricaFaculty of Medicine, Department of Internal Medicine, University of Botswana and Department of Medicine, Princess Marina Hospital, Gaborone, BotswanaBackground: Diabetes mellitus (DM) is a major global public health problem. Lack of adherence to medication causes suboptimal glycemic control increasing complication rates, costs and mortality. The objective of the study was to determine current antidiabetic medication adherence in Botswana and assess associated factors so as to direct potential future interventions. Materials and methods: A cross-sectional study among 376 randomly selected diabetic patients attending a leading clinic in Gaborone, Botswana. Eight item Morisky Medication adherence questionnaire was used to assess antidiabetic medication adherence. A structured questionnaire was also used to collect information on factors influencing adherence including age, gender, education, type and duration of diabetes, treatment, complications and HIV status. Data were entered and analyzed using STATA Version 14, and logistic regression performed. Results: Over forty percent (41.8%) of patients were non-adherent to antidiabetic medications. Studied sociodemographic characteristics and clinical variables did not affect adherence. HIV positive status was associated with a statistically significant better adherence at multivariate analysis. Conclusion: Adherence to antidiabetic medication was found to be suboptimal in a setting where medicines are provided free of charge. Only HIV positivity was found to be significantly associated with better adherence, probably due to effect of greater psychosocial support and counselling as part of HIV treatment. There is a need to carry out studies to further improve understanding of factors associated with medication adherence that are pertinent to Botswana and similar settings given the growing prevalence of diabetes.http://www.sciencedirect.com/science/article/pii/S2090506817300064 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Godfrey Mutashambara Rwegerera Thato Moshomo Marea Gaenamong Taibat Aderonke Oyewo Sivasomnath Gollakota Francis Apolinary Mhimbira Joseph Fadare Brian Godman Johanna C. Meyer Yordanka Piña Rivera |
spellingShingle |
Godfrey Mutashambara Rwegerera Thato Moshomo Marea Gaenamong Taibat Aderonke Oyewo Sivasomnath Gollakota Francis Apolinary Mhimbira Joseph Fadare Brian Godman Johanna C. Meyer Yordanka Piña Rivera Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future Alexandria Journal of Medicine |
author_facet |
Godfrey Mutashambara Rwegerera Thato Moshomo Marea Gaenamong Taibat Aderonke Oyewo Sivasomnath Gollakota Francis Apolinary Mhimbira Joseph Fadare Brian Godman Johanna C. Meyer Yordanka Piña Rivera |
author_sort |
Godfrey Mutashambara Rwegerera |
title |
Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future |
title_short |
Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future |
title_full |
Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future |
title_fullStr |
Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future |
title_full_unstemmed |
Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future |
title_sort |
antidiabetic medication adherence and associated factors among patients in botswana; implications for the future |
publisher |
Taylor & Francis Group |
series |
Alexandria Journal of Medicine |
issn |
2090-5068 |
publishDate |
2018-06-01 |
description |
Background: Diabetes mellitus (DM) is a major global public health problem. Lack of adherence to medication causes suboptimal glycemic control increasing complication rates, costs and mortality. The objective of the study was to determine current antidiabetic medication adherence in Botswana and assess associated factors so as to direct potential future interventions. Materials and methods: A cross-sectional study among 376 randomly selected diabetic patients attending a leading clinic in Gaborone, Botswana. Eight item Morisky Medication adherence questionnaire was used to assess antidiabetic medication adherence. A structured questionnaire was also used to collect information on factors influencing adherence including age, gender, education, type and duration of diabetes, treatment, complications and HIV status. Data were entered and analyzed using STATA Version 14, and logistic regression performed. Results: Over forty percent (41.8%) of patients were non-adherent to antidiabetic medications. Studied sociodemographic characteristics and clinical variables did not affect adherence. HIV positive status was associated with a statistically significant better adherence at multivariate analysis. Conclusion: Adherence to antidiabetic medication was found to be suboptimal in a setting where medicines are provided free of charge. Only HIV positivity was found to be significantly associated with better adherence, probably due to effect of greater psychosocial support and counselling as part of HIV treatment. There is a need to carry out studies to further improve understanding of factors associated with medication adherence that are pertinent to Botswana and similar settings given the growing prevalence of diabetes. |
url |
http://www.sciencedirect.com/science/article/pii/S2090506817300064 |
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