Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis
Alveolar bone ridge resorption occurred after natural teeth loss and it can restrict the possibility of dental implants placement. The use of bone regenerative procedures is frequently required. The existing evidence regarding the efficacy of horizontal bone ridge augmentation trough guided bone reg...
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doaj-a8c8878e895b4ae5bd5fcf3ffb4f23302021-04-06T23:03:43ZengMDPI AGPolymers2073-43602021-04-01131172117210.3390/polym13071172Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-AnalysisManuel Toledano-Osorio0Manuel Toledano1Francisco Javier Manzano-Moreno2Cristina Vallecillo3Marta Vallecillo-Rivas4Alberto Rodriguez-Archilla5Raquel Osorio6Colegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, SpainColegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, SpainBiomedical Group (BIO277), Department of Stomatology, School of Dentistry, University of Granada, 18071 Granada, SpainColegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, SpainColegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, SpainColegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, SpainColegio Máximo de Cartuja s/n, Faculty of Dentistry, University of Granada, 18071 Granada, SpainAlveolar bone ridge resorption occurred after natural teeth loss and it can restrict the possibility of dental implants placement. The use of bone regenerative procedures is frequently required. The existing evidence regarding the efficacy of horizontal bone ridge augmentation trough guided bone regeneration (GBR) using polymeric membranes was stated. A systematic review and meta-analysis were performed. Electronic and manual literature searches were conducted. Screening process was done using the National Library of Medicine (MEDLINE by PubMed), Embase, and the Cochrane Oral Health. Included articles were randomized controlled trials and observational studies. Weighted means were calculated. Heterogeneity was determined using Higgins (<i>I</i>2). If I2 > 50% a random-effects model was applied. It was found that the mean of horizontal bone gain was 3.95 mm, ranging from 3.19 to 4.70 mm (confidence interval 95%). Heterogeneity is I2 = 99% (confidence interval 95%) and significance of the random-effects model was <i>p</i> < 0.001. The complications rate was 8.4% and membrane exposure was the most frequent. Through this study, we were able to conclude that the existing scientific evidence suggests that GBR using polymeric membranes is a predictable technique for achieving horizontal bone augmentation, thus, permitting a proper further implant placement.https://www.mdpi.com/2073-4360/13/7/1172bone regenerationpolymeric membranebone substitutesridge augmentation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Manuel Toledano-Osorio Manuel Toledano Francisco Javier Manzano-Moreno Cristina Vallecillo Marta Vallecillo-Rivas Alberto Rodriguez-Archilla Raquel Osorio |
spellingShingle |
Manuel Toledano-Osorio Manuel Toledano Francisco Javier Manzano-Moreno Cristina Vallecillo Marta Vallecillo-Rivas Alberto Rodriguez-Archilla Raquel Osorio Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis Polymers bone regeneration polymeric membrane bone substitutes ridge augmentation |
author_facet |
Manuel Toledano-Osorio Manuel Toledano Francisco Javier Manzano-Moreno Cristina Vallecillo Marta Vallecillo-Rivas Alberto Rodriguez-Archilla Raquel Osorio |
author_sort |
Manuel Toledano-Osorio |
title |
Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis |
title_short |
Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis |
title_full |
Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis |
title_fullStr |
Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis |
title_full_unstemmed |
Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis |
title_sort |
alveolar bone ridge augmentation using polymeric membranes: a systematic review and meta-analysis |
publisher |
MDPI AG |
series |
Polymers |
issn |
2073-4360 |
publishDate |
2021-04-01 |
description |
Alveolar bone ridge resorption occurred after natural teeth loss and it can restrict the possibility of dental implants placement. The use of bone regenerative procedures is frequently required. The existing evidence regarding the efficacy of horizontal bone ridge augmentation trough guided bone regeneration (GBR) using polymeric membranes was stated. A systematic review and meta-analysis were performed. Electronic and manual literature searches were conducted. Screening process was done using the National Library of Medicine (MEDLINE by PubMed), Embase, and the Cochrane Oral Health. Included articles were randomized controlled trials and observational studies. Weighted means were calculated. Heterogeneity was determined using Higgins (<i>I</i>2). If I2 > 50% a random-effects model was applied. It was found that the mean of horizontal bone gain was 3.95 mm, ranging from 3.19 to 4.70 mm (confidence interval 95%). Heterogeneity is I2 = 99% (confidence interval 95%) and significance of the random-effects model was <i>p</i> < 0.001. The complications rate was 8.4% and membrane exposure was the most frequent. Through this study, we were able to conclude that the existing scientific evidence suggests that GBR using polymeric membranes is a predictable technique for achieving horizontal bone augmentation, thus, permitting a proper further implant placement. |
topic |
bone regeneration polymeric membrane bone substitutes ridge augmentation |
url |
https://www.mdpi.com/2073-4360/13/7/1172 |
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