Relevance of Bacteriophage 933W in the Development of Hemolytic Uremic Syndrome (HUS)

Hemolytic uremic syndrome (HUS), principally caused by shiga toxins (Stxs), is associated with Shiga toxin-producing Escherichia coli (STEC) infections. We previously reported Stx2 expression by host cells in vitro and in vivo. As the genes encoding the two Stx subunits are located in bacteriophage...

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Main Authors: Manuel E. Del Cogliano, Alipio Pinto, Jorge Goldstein, Elsa Zotta, Federico Ochoa, Romina Jimena Fernández-Brando, Maite Muniesa, Pablo D. Ghiringhelli, Marina S. Palermo, Leticia V. Bentancor
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03104/full