Relevance of Bacteriophage 933W in the Development of Hemolytic Uremic Syndrome (HUS)

Relevance of Bacteriophage 933W in the Development of Hemolytic Uremic Syndrome (HUS)

Hemolytic uremic syndrome (HUS), principally caused by shiga toxins (Stxs), is associated with Shiga toxin-producing Escherichia coli (STEC) infections. We previously reported Stx2 expression by host cells in vitro and in vivo. As the genes encoding the two Stx subunits are located in bacteriophage...

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Bibliographic Details
Main Authors: Manuel E. Del Cogliano, Alipio Pinto, Jorge Goldstein, Elsa Zotta, Federico Ochoa, Romina Jimena Fernández-Brando, Maite Muniesa, Pablo D. Ghiringhelli, Marina S. Palermo, Leticia V. Bentancor
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Microbiology
Subjects:
bacterio(phages)
hemolytic uremic syndrome
Shiga toxin (Stx)
Shiga toxigenic E. coli (STEC)
animal model
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.03104/full

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