Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
A wealth of gene expression data is publicly available, yet is little use without additional human curation. Ma’ayan and colleagues report a crowdsourcing project involving over 70 participants to annotate and analyse thousands of human disease-related gene expression datasets.
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12846 |
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Article |
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DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Zichen Wang Caroline D. Monteiro Kathleen M. Jagodnik Nicolas F. Fernandez Gregory W. Gundersen Andrew D. Rouillard Sherry L. Jenkins Axel S. Feldmann Kevin S. Hu Michael G. McDermott Qiaonan Duan Neil R. Clark Matthew R. Jones Yan Kou Troy Goff Holly Woodland Fabio M R. Amaral Gregory L. Szeto Oliver Fuchs Sophia M. Schüssler-Fiorenza Rose Shvetank Sharma Uwe Schwartz Xabier Bengoetxea Bausela Maciej Szymkiewicz Vasileios Maroulis Anton Salykin Carolina M. Barra Candice D. Kruth Nicholas J. Bongio Vaibhav Mathur Radmila D Todoric Udi E. Rubin Apostolos Malatras Carl T. Fulp John A. Galindo Ruta Motiejunaite Christoph Jüschke Philip C. Dishuck Katharina Lahl Mohieddin Jafari Sara Aibar Apostolos Zaravinos Linda H. Steenhuizen Lindsey R. Allison Pablo Gamallo Fernando de Andres Segura Tyler Dae Devlin Vicente Pérez-García Avi Ma’ayan |
| spellingShingle |
Zichen Wang Caroline D. Monteiro Kathleen M. Jagodnik Nicolas F. Fernandez Gregory W. Gundersen Andrew D. Rouillard Sherry L. Jenkins Axel S. Feldmann Kevin S. Hu Michael G. McDermott Qiaonan Duan Neil R. Clark Matthew R. Jones Yan Kou Troy Goff Holly Woodland Fabio M R. Amaral Gregory L. Szeto Oliver Fuchs Sophia M. Schüssler-Fiorenza Rose Shvetank Sharma Uwe Schwartz Xabier Bengoetxea Bausela Maciej Szymkiewicz Vasileios Maroulis Anton Salykin Carolina M. Barra Candice D. Kruth Nicholas J. Bongio Vaibhav Mathur Radmila D Todoric Udi E. Rubin Apostolos Malatras Carl T. Fulp John A. Galindo Ruta Motiejunaite Christoph Jüschke Philip C. Dishuck Katharina Lahl Mohieddin Jafari Sara Aibar Apostolos Zaravinos Linda H. Steenhuizen Lindsey R. Allison Pablo Gamallo Fernando de Andres Segura Tyler Dae Devlin Vicente Pérez-García Avi Ma’ayan Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd Nature Communications |
| author_facet |
Zichen Wang Caroline D. Monteiro Kathleen M. Jagodnik Nicolas F. Fernandez Gregory W. Gundersen Andrew D. Rouillard Sherry L. Jenkins Axel S. Feldmann Kevin S. Hu Michael G. McDermott Qiaonan Duan Neil R. Clark Matthew R. Jones Yan Kou Troy Goff Holly Woodland Fabio M R. Amaral Gregory L. Szeto Oliver Fuchs Sophia M. Schüssler-Fiorenza Rose Shvetank Sharma Uwe Schwartz Xabier Bengoetxea Bausela Maciej Szymkiewicz Vasileios Maroulis Anton Salykin Carolina M. Barra Candice D. Kruth Nicholas J. Bongio Vaibhav Mathur Radmila D Todoric Udi E. Rubin Apostolos Malatras Carl T. Fulp John A. Galindo Ruta Motiejunaite Christoph Jüschke Philip C. Dishuck Katharina Lahl Mohieddin Jafari Sara Aibar Apostolos Zaravinos Linda H. Steenhuizen Lindsey R. Allison Pablo Gamallo Fernando de Andres Segura Tyler Dae Devlin Vicente Pérez-García Avi Ma’ayan |
| author_sort |
Zichen Wang |
| title |
Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd |
| title_short |
Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd |
| title_full |
Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd |
| title_fullStr |
Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd |
| title_full_unstemmed |
Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd |
| title_sort |
extraction and analysis of signatures from the gene expression omnibus by the crowd |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-09-01 |
| description |
A wealth of gene expression data is publicly available, yet is little use without additional human curation. Ma’ayan and colleagues report a crowdsourcing project involving over 70 participants to annotate and analyse thousands of human disease-related gene expression datasets. |
| url |
https://doi.org/10.1038/ncomms12846 |
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doaj-a8f2b28d890e4a0e99fc75b9634da8c02021-05-11T10:35:03ZengNature Publishing GroupNature Communications2041-17232016-09-017111110.1038/ncomms12846Extraction and analysis of signatures from the Gene Expression Omnibus by the crowdZichen Wang0Caroline D. Monteiro1Kathleen M. Jagodnik2Nicolas F. Fernandez3Gregory W. Gundersen4Andrew D. Rouillard5Sherry L. Jenkins6Axel S. Feldmann7Kevin S. Hu8Michael G. McDermott9Qiaonan Duan10Neil R. Clark11Matthew R. Jones12Yan Kou13Troy Goff14Holly Woodland15Fabio M R. Amaral16Gregory L. Szeto17Oliver Fuchs18Sophia M. Schüssler-Fiorenza Rose19Shvetank Sharma20Uwe Schwartz21Xabier Bengoetxea Bausela22Maciej Szymkiewicz23Vasileios MaroulisAnton Salykin24Carolina M. Barra25Candice D. KruthNicholas J. Bongio26Vaibhav Mathur27Radmila D TodoricUdi E. Rubin28Apostolos Malatras29Carl T. FulpJohn A. Galindo30Ruta Motiejunaite31Christoph Jüschke32Philip C. DishuckKatharina Lahl33Mohieddin Jafari34Sara Aibar35Apostolos Zaravinos36Linda H. Steenhuizen37Lindsey R. AllisonPablo GamalloFernando de Andres Segura38Tyler Dae DevlinVicente Pérez-García39Avi Ma’ayan40Department of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiDaylesford, the FairwaySchool of Biosciences, University of Nottingham, Sutton Bonington CampusDepartment of Biological Engineering, Massachusetts Institute of TechnologyPaediatric Allergology and Pulmonology, Dr von Hauner University Children’s Hospital, Ludwig-Maximilians-University of Munich, Member of the German Centre for Lung Research (DZL)Spinal Cord Injury Service, Veteran Affairs Palo Alto Health Care SystemDepartment of Research, Institute of Liver & Biliary SciencesDepartment of Biochemistry III, University of RegensburgDepartment of Pharmacology and Toxicology, University of NavarraWarsaw School of Information Technology under the auspices of the Polish Academy of SciencesDepartment of Biology, Faculty of Medicine, Masaryk UniversityIMIM-Hospital Del Mar, PRBB Barcelona, Dr AiguaderDepartment of Biology, Shenandoah UniversityIBM India Pvt Ltd.Department of Biological SciencesCenter for Research in Myology, Sorbonne Universités, UPMC Univ Paris 06, INSERM UMRS975, CNRS FRE3617Department of Biology and Institute of Genetics, Universidad Nacional de ColombiaCenter for Interdisciplinary Cardiovascular Sciences, Brigham and Women’s HospitalDepartment of Human Genetics, Faculty of Medicine and Health Sciences, University of OldenburgTechnical University of Denmark, National Veterinary InstituteProtein Chemistry and Proteomics Unit, Biotechnology Research Center, Pasteur Institute of IranUniversity of SalamancaDivision of Clinical Immunology, Department of Laboratory Medicine, Karolinska InstituteAnna Blamansingel 216CICAB, Clinical Research Centre, Extremadura University HospitalDepartment of Immunology and Oncology, Consejo Superior de Investigaciones Científicas, Centro Nacional de BiotecnologíaDepartment of Pharmacological Sciences, BD2K-LINCS Data Coordination and Integration Center, Illuminating the Druggable Genome Knowledge Management Center, Icahn School of Medicine at Mount SinaiA wealth of gene expression data is publicly available, yet is little use without additional human curation. Ma’ayan and colleagues report a crowdsourcing project involving over 70 participants to annotate and analyse thousands of human disease-related gene expression datasets.https://doi.org/10.1038/ncomms12846 |