The effect of depression and health-related quality of life on the outcome of hemodialysis patients
Background: In hemodialysis (HD) patients, traditional risk factors cannot explain all of the mortality and morbidity. This study was designed to investigate the effect of depression and health-related quality of life (HRQOL) on prognosis in maintenance HD patients. Methods: In February 2008, the Be...
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The Korean Society of Nephrology
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doaj-a8f80bfa153948008fe1ed8d3c7448a12020-11-24T21:08:05ZengThe Korean Society of NephrologyKidney Research and Clinical Practice2211-91322012-03-01311546110.1016/j.krcp.2012.01.001The effect of depression and health-related quality of life on the outcome of hemodialysis patientsHee Jung Jeon0Hayne Cho Park1Ji In Park2Jung Pyo Lee3Kook-Hwan Oh4Ho Jun Chin5Kwon Wook Joo6Yon Su Kim7Chun Soo Lim8Curie Ahn9Jin Suk Han10Suhnggwon Kim11Yun Kyu Oh12Department of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, KoreaBackground: In hemodialysis (HD) patients, traditional risk factors cannot explain all of the mortality and morbidity. This study was designed to investigate the effect of depression and health-related quality of life (HRQOL) on prognosis in maintenance HD patients. Methods: In February 2008, the Beck's Depression Inventory and the Kidney Dialysis Quality of Life—Short Form were utilized to measure depression and HRQOL. Until February 2011, the mortality, cardiovascular events, infection, and hospitalization were investigated, retrospectively. Results: Among the 166 patients, the 3-year cumulative survival rate was 88.8%, and the depression did not affect survival (depression vs. nondepression: 91.8% vs. 87.2%, P=0.437). The upper tertiles in physical component summary (PCS) were correlated with lower mortality (OR, 0.12; P=0.05) and fewer cardiovascular events (OR, 0.09; P=0.024) than the lower tertiles. The upper tertiles in kidney disease component summary (KDCS) were associated with less hospitalization than the lower tertiles (OR, 0.38; P=0.024). After adjusting for multiple variables including age, comorbidity index, and albumin, upper tertiles in PCS were correlated with fewer cardiovascular events than the lower tertiles (OR, 0.08; P=0.038). Conclusion: The cross-sectional survey of whether HD patients had depression was not significantly associated with mortality and morbidity. HRQOL was correlated with mortality, cardiovascular events and hospitalization.http://www.sciencedirect.com/science/article/pii/S2211913212000101DepressionHemodialysisOutcomeQuality of life |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hee Jung Jeon Hayne Cho Park Ji In Park Jung Pyo Lee Kook-Hwan Oh Ho Jun Chin Kwon Wook Joo Yon Su Kim Chun Soo Lim Curie Ahn Jin Suk Han Suhnggwon Kim Yun Kyu Oh |
spellingShingle |
Hee Jung Jeon Hayne Cho Park Ji In Park Jung Pyo Lee Kook-Hwan Oh Ho Jun Chin Kwon Wook Joo Yon Su Kim Chun Soo Lim Curie Ahn Jin Suk Han Suhnggwon Kim Yun Kyu Oh The effect of depression and health-related quality of life on the outcome of hemodialysis patients Kidney Research and Clinical Practice Depression Hemodialysis Outcome Quality of life |
author_facet |
Hee Jung Jeon Hayne Cho Park Ji In Park Jung Pyo Lee Kook-Hwan Oh Ho Jun Chin Kwon Wook Joo Yon Su Kim Chun Soo Lim Curie Ahn Jin Suk Han Suhnggwon Kim Yun Kyu Oh |
author_sort |
Hee Jung Jeon |
title |
The effect of depression and health-related quality of life on the outcome of hemodialysis patients |
title_short |
The effect of depression and health-related quality of life on the outcome of hemodialysis patients |
title_full |
The effect of depression and health-related quality of life on the outcome of hemodialysis patients |
title_fullStr |
The effect of depression and health-related quality of life on the outcome of hemodialysis patients |
title_full_unstemmed |
The effect of depression and health-related quality of life on the outcome of hemodialysis patients |
title_sort |
effect of depression and health-related quality of life on the outcome of hemodialysis patients |
publisher |
The Korean Society of Nephrology |
series |
Kidney Research and Clinical Practice |
issn |
2211-9132 |
publishDate |
2012-03-01 |
description |
Background: In hemodialysis (HD) patients, traditional risk factors cannot explain all of the mortality and morbidity. This study was designed to investigate the effect of depression and health-related quality of life (HRQOL) on prognosis in maintenance HD patients.
Methods: In February 2008, the Beck's Depression Inventory and the Kidney Dialysis Quality of Life—Short Form were utilized to measure depression and HRQOL. Until February 2011, the mortality, cardiovascular events, infection, and hospitalization were investigated, retrospectively.
Results: Among the 166 patients, the 3-year cumulative survival rate was 88.8%, and the depression did not affect survival (depression vs. nondepression: 91.8% vs. 87.2%, P=0.437). The upper tertiles in physical component summary (PCS) were correlated with lower mortality (OR, 0.12; P=0.05) and fewer cardiovascular events (OR, 0.09; P=0.024) than the lower tertiles. The upper tertiles in kidney disease component summary (KDCS) were associated with less hospitalization than the lower tertiles (OR, 0.38; P=0.024). After adjusting for multiple variables including age, comorbidity index, and albumin, upper tertiles in PCS were correlated with fewer cardiovascular events than the lower tertiles (OR, 0.08; P=0.038).
Conclusion: The cross-sectional survey of whether HD patients had depression was not significantly associated with mortality and morbidity. HRQOL was correlated with mortality, cardiovascular events and hospitalization. |
topic |
Depression Hemodialysis Outcome Quality of life |
url |
http://www.sciencedirect.com/science/article/pii/S2211913212000101 |
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