Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study
Introduction: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. Objective: To compare the evolution of th...
Main Authors: | , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-12-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/7/12/509 |
id |
doaj-a9038e8aca2b42f18ccd7ea803a45449 |
---|---|
record_format |
Article |
spelling |
doaj-a9038e8aca2b42f18ccd7ea803a454492020-11-25T00:45:50ZengMDPI AGJournal of Clinical Medicine2077-03832018-12-0171250910.3390/jcm7120509jcm7120509Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd StudyAurélie Loyeau0Hakim Benamer1Sophie Bataille2Sarah Tepper3Thévy Boche4Lionel Lamhaut5Virginie Pirès6Benoit Simon7François Dupas8Lisa Weisslinger9Gaëlle Le Bail10Alexandre Allonneau11Jean-Michel Juliard12Yves Lambert13Frédéric Lapostolle14Registry Department, Regional Health Agency in Great Paris Area, 75008 Paris, FranceRamsay Générale de Santé, ICPS, 6 Avenue du Noyer Lambert à Massy, 91300 Massy, FranceRegistry Department, Regional Health Agency in Great Paris Area, 75008 Paris, FranceSAMU 93, UF Recherche-Enseignement-Qualité Avicenne Hospital-APHP, 93000 Bobigny, FranceSAMU 94 Mondor Hospital-APHP, 94000 Créteil, FranceSAMU 94 Mondor Hospital-APHP, 94000 Créteil, FranceSAMU 77, Melun Hospital, 77000 Melun, FranceSAMU 91, Sud Francilien Hospital, 91100 Corbeil-Essonnes, FranceSAMU 95, Pontoise Hospital, 95032 Pontoise, FranceSAMU 93, UF Recherche-Enseignement-Qualité Avicenne Hospital-APHP, 93000 Bobigny, FranceSAMU 92, Garches Hospital-APHP, 92380 Garches, FranceFire Departement of Paris, EMS Department, 75008 Paris, FranceCardiology Department, DHU FIRE, Université Paris Diderot, Sorbonne Paris-Cité, INSERM U-1148, Bichat Hospital-APHP, 75008 Paris, FranceSAMU 78, Versailles Hospital, 78150 Le Chesnay, FranceSAMU 93, UF Recherche-Enseignement-Qualité Avicenne Hospital-APHP, 93000 Bobigny, FranceIntroduction: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. Objective: To compare the evolution of the age pyramid of patients with ST-elevation myocardial infarction (STEMI) according to gender. Methods: Data from patients with STEMI managed in pre-hospital settings prospectively collected in the greater Paris area. Evolution of patient demographics and risk factors was investigated. Results: 28,249 patients with STEMI were included in the registry between 2002 and 2014, 21,883 (77%) males and 6366 (23%) females. The sex ratio did not significantly vary over the study period (<i>p</i> = 0.4). Median patient age was 60.1 years (51.1–73.0) and was significantly different between males and females, respectively 57.9 (50.0–68.3) vs. 72.9 years (58.3–82.2) (<i>p</i> = 0.0004). The median age of males significantly (<i>p</i> = 0.0044) increased from 57.6 (50.1–70.0) in 2002 to 58.1 years (50.5–67.8) in 2014. The median age of females significantly (<i>p</i> = 0.0006) decreased from 73.7 (57.9–81.8) to 69.6 years (57.0–82.4). The median gap between the age of men and women significantly (<i>p</i> = 0.0002) decreased, from 16.1 to 11.5 years. Prevalence of risk factors was unchanged or decreased except for hypertension which significantly increased in males. The rate of STEMI without reported risk factors increased in both males and females. Conclusion: The age of STEMI onset significantly decreased in females, whereas it significantly increased in males. The prevalence of risk factors decreased in males, whereas no significant variation was found in females.https://www.mdpi.com/2077-0383/7/12/509ST-elevation myocardial infarction (STEMI)prehospitalgenderageage pyramid |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Aurélie Loyeau Hakim Benamer Sophie Bataille Sarah Tepper Thévy Boche Lionel Lamhaut Virginie Pirès Benoit Simon François Dupas Lisa Weisslinger Gaëlle Le Bail Alexandre Allonneau Jean-Michel Juliard Yves Lambert Frédéric Lapostolle |
spellingShingle |
Aurélie Loyeau Hakim Benamer Sophie Bataille Sarah Tepper Thévy Boche Lionel Lamhaut Virginie Pirès Benoit Simon François Dupas Lisa Weisslinger Gaëlle Le Bail Alexandre Allonneau Jean-Michel Juliard Yves Lambert Frédéric Lapostolle Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study Journal of Clinical Medicine ST-elevation myocardial infarction (STEMI) prehospital gender age age pyramid |
author_facet |
Aurélie Loyeau Hakim Benamer Sophie Bataille Sarah Tepper Thévy Boche Lionel Lamhaut Virginie Pirès Benoit Simon François Dupas Lisa Weisslinger Gaëlle Le Bail Alexandre Allonneau Jean-Michel Juliard Yves Lambert Frédéric Lapostolle |
author_sort |
Aurélie Loyeau |
title |
Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study |
title_short |
Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study |
title_full |
Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study |
title_fullStr |
Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study |
title_full_unstemmed |
Evolution of ST-Elevation Acute Myocardial Infarction Prevalence by Gender Assessed Age Pyramid Analysis—The Piramyd Study |
title_sort |
evolution of st-elevation acute myocardial infarction prevalence by gender assessed age pyramid analysis—the piramyd study |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2018-12-01 |
description |
Introduction: Recent studies reported a decrease in the incidence of acute myocardial infarction. This favorable evolution does not extend to young women. The interaction between gender, risk factors and myocardial infarction incidence remains controversial. Objective: To compare the evolution of the age pyramid of patients with ST-elevation myocardial infarction (STEMI) according to gender. Methods: Data from patients with STEMI managed in pre-hospital settings prospectively collected in the greater Paris area. Evolution of patient demographics and risk factors was investigated. Results: 28,249 patients with STEMI were included in the registry between 2002 and 2014, 21,883 (77%) males and 6366 (23%) females. The sex ratio did not significantly vary over the study period (<i>p</i> = 0.4). Median patient age was 60.1 years (51.1–73.0) and was significantly different between males and females, respectively 57.9 (50.0–68.3) vs. 72.9 years (58.3–82.2) (<i>p</i> = 0.0004). The median age of males significantly (<i>p</i> = 0.0044) increased from 57.6 (50.1–70.0) in 2002 to 58.1 years (50.5–67.8) in 2014. The median age of females significantly (<i>p</i> = 0.0006) decreased from 73.7 (57.9–81.8) to 69.6 years (57.0–82.4). The median gap between the age of men and women significantly (<i>p</i> = 0.0002) decreased, from 16.1 to 11.5 years. Prevalence of risk factors was unchanged or decreased except for hypertension which significantly increased in males. The rate of STEMI without reported risk factors increased in both males and females. Conclusion: The age of STEMI onset significantly decreased in females, whereas it significantly increased in males. The prevalence of risk factors decreased in males, whereas no significant variation was found in females. |
topic |
ST-elevation myocardial infarction (STEMI) prehospital gender age age pyramid |
url |
https://www.mdpi.com/2077-0383/7/12/509 |
work_keys_str_mv |
AT aurelieloyeau evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT hakimbenamer evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT sophiebataille evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT sarahtepper evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT thevyboche evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT lionellamhaut evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT virginiepires evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT benoitsimon evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT francoisdupas evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT lisaweisslinger evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT gaellelebail evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT alexandreallonneau evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT jeanmicheljuliard evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT yveslambert evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy AT fredericlapostolle evolutionofstelevationacutemyocardialinfarctionprevalencebygenderassessedagepyramidanalysisthepiramydstudy |
_version_ |
1725268620188057600 |