Characterization of the hemodynamic response function in white matter tracts for event-related fMRI

Characterization of the hemodynamic response function in white matter tracts for event-related fMRI

The hemodynamic response function (HRF) describes how changes in brain activity manifest as a transient signal (BOLD) that is detected by fMRI imaging. Here, the authors show that the HRF in white matter shows reduced magnitudes, delayed onsets, and prolonged initial dips compared to the grey matter...

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Main Authors: Muwei Li, Allen T. Newton, Adam W. Anderson, Zhaohua Ding, John C. Gore
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09076-2
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spelling doaj-a90b2001dd0e4c06a3607a91fa32e8472021-05-11T11:48:59ZengNature Publishing GroupNature Communications2041-17232019-03-0110111110.1038/s41467-019-09076-2Characterization of the hemodynamic response function in white matter tracts for event-related fMRIMuwei Li0Allen T. Newton1Adam W. Anderson2Zhaohua Ding3John C. Gore4Vanderbilt University Institute of Imaging ScienceVanderbilt University Institute of Imaging ScienceVanderbilt University Institute of Imaging ScienceVanderbilt University Institute of Imaging ScienceVanderbilt University Institute of Imaging ScienceThe hemodynamic response function (HRF) describes how changes in brain activity manifest as a transient signal (BOLD) that is detected by fMRI imaging. Here, the authors show that the HRF in white matter shows reduced magnitudes, delayed onsets, and prolonged initial dips compared to the grey matter HRF.https://doi.org/10.1038/s41467-019-09076-2
collection DOAJ
language English
format Article
sources DOAJ
author Muwei Li
Allen T. Newton
Adam W. Anderson
Zhaohua Ding
John C. Gore
spellingShingle Muwei Li
Allen T. Newton
Adam W. Anderson
Zhaohua Ding
John C. Gore
Characterization of the hemodynamic response function in white matter tracts for event-related fMRI
Nature Communications
author_facet Muwei Li
Allen T. Newton
Adam W. Anderson
Zhaohua Ding
John C. Gore
author_sort Muwei Li
title Characterization of the hemodynamic response function in white matter tracts for event-related fMRI
title_short Characterization of the hemodynamic response function in white matter tracts for event-related fMRI
title_full Characterization of the hemodynamic response function in white matter tracts for event-related fMRI
title_fullStr Characterization of the hemodynamic response function in white matter tracts for event-related fMRI
title_full_unstemmed Characterization of the hemodynamic response function in white matter tracts for event-related fMRI
title_sort characterization of the hemodynamic response function in white matter tracts for event-related fmri
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-03-01
description The hemodynamic response function (HRF) describes how changes in brain activity manifest as a transient signal (BOLD) that is detected by fMRI imaging. Here, the authors show that the HRF in white matter shows reduced magnitudes, delayed onsets, and prolonged initial dips compared to the grey matter HRF.
url https://doi.org/10.1038/s41467-019-09076-2
work_keys_str_mv AT muweili characterizationofthehemodynamicresponsefunctioninwhitemattertractsforeventrelatedfmri
AT allentnewton characterizationofthehemodynamicresponsefunctioninwhitemattertractsforeventrelatedfmri
AT adamwanderson characterizationofthehemodynamicresponsefunctioninwhitemattertractsforeventrelatedfmri
AT zhaohuading characterizationofthehemodynamicresponsefunctioninwhitemattertractsforeventrelatedfmri
AT johncgore characterizationofthehemodynamicresponsefunctioninwhitemattertractsforeventrelatedfmri
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