Sub-paresthesia spinal cord stimulation reverses thermal hyperalgesia and modulates low frequency EEG in a rat model of neuropathic pain
Abstract Paresthesia, a common feature of epidural spinal cord stimulation (SCS) for pain management, presents a challenge to the double-blind study design. Although sub-paresthesia SCS has been shown to be effective in alleviating pain, empirical criteria for sub-paresthesia SCS have not been estab...
Main Authors: | Suguru Koyama, Jimmy Xia, Brian W. Leblanc, Jianwen Wendy Gu, Carl Y. Saab |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-05-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-25420-w |
Similar Items
-
Blocking spinal CCR2 with AZ889 reversed hyperalgesia in a model of neuropathic pain
by: Vaillancourt François, et al.
Published: (2010-12-01) -
Spinal cord stimulation for neuropathic pain: current perspectives
by: Wolter T
Published: (2014-11-01) -
Pre-injury administration of morphine prevents development of neuropathic hyperalgesia through activation of descending monoaminergic mechanisms in the spinal cord in mice
by: Rashid Md Harunor, et al.
Published: (2005-06-01) -
Long-Lasting Effect of Transcranial Direct Current Stimulation in the Reversal of Hyperalgesia and Cytokine Alterations Induced by the Neuropathic Pain Model
by: Stefania Giotti Cioato, et al.
Published: (2016-03-01) -
SPINAL CORD STIMULATION IN TREATMENT OF THE NEUROPATHIC PAIN SYNDROMES: INITIAL EXPERIENCE
by: D. A. Rzaev, et al.
Published: (2016-11-01)