The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats

Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. This study was designed...

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Main Authors: Aydan Caglayan, Belma Kocer-Gumusel, Pinar Erkekoglu, Filiz Hincal
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_7728_b840f64edfa9104c094c31b9fc70c72c.pdf
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spelling doaj-a91cab1ed0ac4ee9a54fc565f4ed603f2020-11-24T22:45:57ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences 2008-38662008-38742016-10-0119101040104810.22038/ijbms.2016.77287728The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient ratsAydan Caglayan0Belma Kocer-Gumusel1Pinar Erkekoglu2Filiz Hincal3Hacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 TurkeyHacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 TurkeyHacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 TurkeyHacettepe University, Faculty of Pharmacy, Department of Toxicology, Ankara 06100 TurkeyObjective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. This study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme activities in the presence of iodine and/or selenium deficiency on a rat model. Materials and Methods: Iodine and/or selenium deficiency was induced by feeding  three-week-old Wistar rats with a diet containinghttp://ijbms.mums.ac.ir/article_7728_b840f64edfa9104c094c31b9fc70c72c.pdfFenvalerateIodineSeleniumThyroid hormonesXenobiotic metabolizing - enzymes
collection DOAJ
language English
format Article
sources DOAJ
author Aydan Caglayan
Belma Kocer-Gumusel
Pinar Erkekoglu
Filiz Hincal
spellingShingle Aydan Caglayan
Belma Kocer-Gumusel
Pinar Erkekoglu
Filiz Hincal
The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
Iranian Journal of Basic Medical Sciences
Fenvalerate
Iodine
Selenium
Thyroid hormones
Xenobiotic metabolizing - enzymes
author_facet Aydan Caglayan
Belma Kocer-Gumusel
Pinar Erkekoglu
Filiz Hincal
author_sort Aydan Caglayan
title The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
title_short The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
title_full The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
title_fullStr The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
title_full_unstemmed The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
title_sort effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
publisher Mashhad University of Medical Sciences
series Iranian Journal of Basic Medical Sciences
issn 2008-3866
2008-3874
publishDate 2016-10-01
description Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. This study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme activities in the presence of iodine and/or selenium deficiency on a rat model. Materials and Methods: Iodine and/or selenium deficiency was induced by feeding  three-week-old Wistar rats with a diet containing
topic Fenvalerate
Iodine
Selenium
Thyroid hormones
Xenobiotic metabolizing - enzymes
url http://ijbms.mums.ac.ir/article_7728_b840f64edfa9104c094c31b9fc70c72c.pdf
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