Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review
Abstract Background Angioplasty is a fundamental treatment for atherosclerotic disease in the cardiac, cerebrovascular, and peripheral vascular beds. However, the optimal duration of balloon inflation has not been identified. Our study will investigate whether prolonged angioplasty balloon inflation...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-02-01
|
Series: | Systematic Reviews |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13643-019-0955-2 |
id |
doaj-a9209f85d6404659b5e4bd65ecd634ba |
---|---|
record_format |
Article |
spelling |
doaj-a9209f85d6404659b5e4bd65ecd634ba2020-11-25T00:27:35ZengBMCSystematic Reviews2046-40532019-02-01811710.1186/s13643-019-0955-2Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic reviewMark Rockley0Prasad Jetty1George Wells2Kathleen Rockley3Dean Fergusson4Division of Vascular and Endovascular Surgery, Department of Surgery, University of Ottawa, The Ottawa Hospital - Civic CampusDivision of Vascular and Endovascular Surgery, Department of Surgery, University of Ottawa, The Ottawa Hospital - Civic CampusCardiovascular Research Methods Centre, University of Ottawa Heart InstituteDivision of Vascular and Endovascular Surgery, Department of Surgery, University of Ottawa, The Ottawa Hospital - Civic CampusClinical Epidemiology Program, Ottawa Hospital Research InstituteAbstract Background Angioplasty is a fundamental treatment for atherosclerotic disease in the cardiac, cerebrovascular, and peripheral vascular beds. However, the optimal duration of balloon inflation has not been identified. Our study will investigate whether prolonged angioplasty balloon inflation of at least 1 min duration, when compared with brief inflation, affects residual stenosis after arterial angioplasty. Methods In compliance with PRISMA, two independent reviewers will conduct a systematic review of EMBASE, MEDLINE, CENTRAL, trial registries, grey literature, and ancestry and citation search. Data abstraction, quantitative, and quantitative meta-analysis will be performed according to pre-specified criteria. The primary outcome is residual stenosis immediately after initial angioplasty; however, secondary outcomes will include multiple short and long term pre-specific clinical and radiographic outcomes. Risk of bias, subgroup analyses, and sensitivity analyses are planned. Discussion Despite the ubiquitous use of angioplasty in atherosclerotic disease and multiple trials investigating the ideal balloon inflation duration, there are no systematic reviews evaluating prolonged angioplasty balloon inflation. Currently synthesized evidence is insufficient to confidently direct clinical decision-making, and the current variation in operator preference of balloon angioplasty duration suggests ongoing clinical equipoise. Given the known availability of current primary evidence, our study intends to synthesize the evidence and guide future clinical decision making and investigation. Systematic review registration PROSPERO CRD42018092702http://link.springer.com/article/10.1186/s13643-019-0955-2AngioplastyDurationProlongedRestenosisArterial patency |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mark Rockley Prasad Jetty George Wells Kathleen Rockley Dean Fergusson |
spellingShingle |
Mark Rockley Prasad Jetty George Wells Kathleen Rockley Dean Fergusson Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review Systematic Reviews Angioplasty Duration Prolonged Restenosis Arterial patency |
author_facet |
Mark Rockley Prasad Jetty George Wells Kathleen Rockley Dean Fergusson |
author_sort |
Mark Rockley |
title |
Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review |
title_short |
Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review |
title_full |
Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review |
title_fullStr |
Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review |
title_full_unstemmed |
Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review |
title_sort |
prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review |
publisher |
BMC |
series |
Systematic Reviews |
issn |
2046-4053 |
publishDate |
2019-02-01 |
description |
Abstract Background Angioplasty is a fundamental treatment for atherosclerotic disease in the cardiac, cerebrovascular, and peripheral vascular beds. However, the optimal duration of balloon inflation has not been identified. Our study will investigate whether prolonged angioplasty balloon inflation of at least 1 min duration, when compared with brief inflation, affects residual stenosis after arterial angioplasty. Methods In compliance with PRISMA, two independent reviewers will conduct a systematic review of EMBASE, MEDLINE, CENTRAL, trial registries, grey literature, and ancestry and citation search. Data abstraction, quantitative, and quantitative meta-analysis will be performed according to pre-specified criteria. The primary outcome is residual stenosis immediately after initial angioplasty; however, secondary outcomes will include multiple short and long term pre-specific clinical and radiographic outcomes. Risk of bias, subgroup analyses, and sensitivity analyses are planned. Discussion Despite the ubiquitous use of angioplasty in atherosclerotic disease and multiple trials investigating the ideal balloon inflation duration, there are no systematic reviews evaluating prolonged angioplasty balloon inflation. Currently synthesized evidence is insufficient to confidently direct clinical decision-making, and the current variation in operator preference of balloon angioplasty duration suggests ongoing clinical equipoise. Given the known availability of current primary evidence, our study intends to synthesize the evidence and guide future clinical decision making and investigation. Systematic review registration PROSPERO CRD42018092702 |
topic |
Angioplasty Duration Prolonged Restenosis Arterial patency |
url |
http://link.springer.com/article/10.1186/s13643-019-0955-2 |
work_keys_str_mv |
AT markrockley prolongedversusbriefballooninflationduringarterialangioplastyfordenovoatheroscleroticdiseaseprotocolforasystematicreview AT prasadjetty prolongedversusbriefballooninflationduringarterialangioplastyfordenovoatheroscleroticdiseaseprotocolforasystematicreview AT georgewells prolongedversusbriefballooninflationduringarterialangioplastyfordenovoatheroscleroticdiseaseprotocolforasystematicreview AT kathleenrockley prolongedversusbriefballooninflationduringarterialangioplastyfordenovoatheroscleroticdiseaseprotocolforasystematicreview AT deanfergusson prolongedversusbriefballooninflationduringarterialangioplastyfordenovoatheroscleroticdiseaseprotocolforasystematicreview |
_version_ |
1725338865856675840 |