MACROD1/LRP16 Enhances LPS-Stimulated Inflammatory Responses by Up-Regulating a Rac1-Dependent Pathway in Adipocytes

Background/Aims: Chronic inflammation contributes to the development of type 2 diabetes mellitus by targeting the insulin receptor substrate protein-1 (IRS-1) signaling pathway. Previous studies showed that Leukemia related protein 16 (LRP16) reduced insulin stimulated glucose uptake in adipocytes b...

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Bibliographic Details
Main Authors: Li Zang, Quan Hong, Guoqing Yang, Weijun Gu, Anping Wang, Jingtao Dou, Yiming Mu, Di Wu, Zhaohui  Lyu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
ERK
Online Access:https://www.karger.com/Article/FullText/495931