Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

Mutations and splice variants in the estrogen receptor (ER) gene, ESR1, may yield endocrine resistance in metastatic breast cancer (MBC) patients. These putative endocrine resistance markers are likely to emerge during treatment, and therefore, its detection in liquid biopsies, such as circulating t...

Full description

Bibliographic Details
Main Authors: Nick Beije, Anieta M. Sieuwerts, Jaco Kraan, Ngoc M. Van, Wendy Onstenk, Silvia R. Vitale, Michelle van derVlugt‐Daane, Luc Y. Dirix, Anja Brouwer, Paul Hamberg, Felix E. deJongh, Agnes Jager, Caroline M. Seynaeve, Maurice P. H. M. Jansen, John A. Foekens, John W. M. Martens, Stefan Sleijfer
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Molecular Oncology
Subjects:
cell‐free DNA
circulating tumor cells
endocrine resistance
ESR1 mutations
Online Access:https://doi.org/10.1002/1878-0261.12147

Internet

https://doi.org/10.1002/1878-0261.12147

Similar Items