Validity of SW982 synovial cell line for studying the drugs against rheumatoid arthritis in fluvastatin-induced apoptosis signaling model

Validity of SW982 synovial cell line for studying the drugs against rheumatoid arthritis in fluvastatin-induced apoptosis signaling model

Background & objectives: To study effects of drugs against rheumatoid arthritis (RA) synoviocytes or fibroblast like synoviocytes (FLS) are used. To overcome the drawbacks of using FLS, this study was conducted to show the validity of SW982 synovial cell line in RA study. Methods: 3-(4,5-dimeth...

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Bibliographic Details
Main Authors: Jae-Ho Chang, Kyu-Jae Lee, Soo-Ki Kim, Dae-Hyun Yoo, Tae-Young Kang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Journal of Medical Research
Subjects:
Apoptosis - fluvastatin - PI3K/Akt - Rac1 - RhoA - SW982 human synovial cells
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=1;spage=117;epage=124;aulast=Chang

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2014;volume=139;issue=1;spage=117;epage=124;aulast=Chang

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