Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs

Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs

PDZ domains constitute a large family of modular domains that are well-known for binding C-terminal motifs of target proteins. Some of them also bind to internal PDZ binding motifs (PDZbms), but this aspect of the PDZ interactome is poorly studied. Here we explored internal PDZbm-mediated interactio...

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Bibliographic Details
Main Authors: Muhammad Ali, Mishal Mariam McAuley, Susanne Lüchow, Stefan Knapp, Andreas C. Joerger, Ylva Ivarsson
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Structural Biology
Subjects:
PDZ domain
Phage display
Short linear motif
SLiM
PDZbm
Shank
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X21000015

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