Sterile keratitis following collagen crosslinking

• Main Authors: Mohammad-Ali Javadi, Sepehr Feizi
• Format: Article
• Language: English
• Published: Knowledge E 2014-01-01
• Series: Journal of Ophthalmic & Vision Research
• Subjects: 510Collagen Crosslinking; Keratoconus; Sterile Keratitis
• Online Access: http://www.jovr.org/article.asp?issn=2008-322X;year=2014;volume=9;issue=4;spage=510;epage=513;aulast=Javadi

Purpose: To report a keratoconic eye that developed severe sterile keratitis and corneal scar after collagen crosslinking necessitating corneal transplantation. Case Report: A 26-year-old man with progressive keratoconus underwent collagen crosslinking and presented with severe keratitis 72 hours after the procedure. The initial impression was infectious corneal ulcer and a fortified antibiotic regimen was administered. However, the clinical course and confocal microscopy results prompted a diagnosis of sterile keratitis. The eye developed severe corneal scars leading to reduced visual acuity and necessitating corneal transplantation. Conclusion: Sterile keratitis may develop after collagen crosslinking resulting in profound visual loss leading to corneal transplantation.