Radial extracorporeal shockwave promotes subchondral bone stem/progenitor cell self-renewal by activating YAP/TAZ and facilitates cartilage repair in vivo

Radial extracorporeal shockwave promotes subchondral bone stem/progenitor cell self-renewal by activating YAP/TAZ and facilitates cartilage repair in vivo

Abstract Background Radial extracorporeal shockwave (r-ESW), an innovative and noninvasive technique, is gaining increasing attention in regenerative medicine due to its mechanobiological effects. Subchondral bone stem/progenitor cells (SCB-SPCs), originating from the pivotal zone of the osteochondr...

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Bibliographic Details
Main Authors: Zhidong Zhao, Yuxing Wang, Qian Wang, Jiawu Liang, Wei Hu, Sen Zhao, Peilin Li, Heng Zhu, Zhongli Li
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Extracorporeal shockwave
Stem/progenitor cells
Self-renewal
Cartilage regeneration
YAP/TAZ
Online Access:https://doi.org/10.1186/s13287-020-02076-w

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