Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells
Circulating memory cells include central memory T cells retaining the ability to enter the lymph nodes whereas tissue resident memory cells are confined to the parenchymal tissues. Here the authors explore the interplay between the two T-cell types and show that both cooperate in anti-tumour immunit...
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2017-07-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms16073 |
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doaj-aa0049fe97b2432095bd04330e3dc3662021-05-11T07:30:07ZengNature Publishing GroupNature Communications2041-17232017-07-018111110.1038/ncomms16073Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cellsMichel Enamorado0Salvador Iborra1Elena Priego2Francisco J. Cueto3Juan A. Quintana4Sarai Martínez-Cano5Ernesto Mejías-Pérez6Mariano Esteban7Ignacio Melero8Andrés Hidalgo9David Sancho10Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Department of Molecular and Cellular Biology, Centro Nacional de BiotecnologíaDepartment of Molecular and Cellular Biology, Centro Nacional de BiotecnologíaDivision of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)Circulating memory cells include central memory T cells retaining the ability to enter the lymph nodes whereas tissue resident memory cells are confined to the parenchymal tissues. Here the authors explore the interplay between the two T-cell types and show that both cooperate in anti-tumour immunity.https://doi.org/10.1038/ncomms16073 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Michel Enamorado Salvador Iborra Elena Priego Francisco J. Cueto Juan A. Quintana Sarai Martínez-Cano Ernesto Mejías-Pérez Mariano Esteban Ignacio Melero Andrés Hidalgo David Sancho |
spellingShingle |
Michel Enamorado Salvador Iborra Elena Priego Francisco J. Cueto Juan A. Quintana Sarai Martínez-Cano Ernesto Mejías-Pérez Mariano Esteban Ignacio Melero Andrés Hidalgo David Sancho Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells Nature Communications |
author_facet |
Michel Enamorado Salvador Iborra Elena Priego Francisco J. Cueto Juan A. Quintana Sarai Martínez-Cano Ernesto Mejías-Pérez Mariano Esteban Ignacio Melero Andrés Hidalgo David Sancho |
author_sort |
Michel Enamorado |
title |
Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells |
title_short |
Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells |
title_full |
Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells |
title_fullStr |
Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells |
title_full_unstemmed |
Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells |
title_sort |
enhanced anti-tumour immunity requires the interplay between resident and circulating memory cd8+ t cells |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2017-07-01 |
description |
Circulating memory cells include central memory T cells retaining the ability to enter the lymph nodes whereas tissue resident memory cells are confined to the parenchymal tissues. Here the authors explore the interplay between the two T-cell types and show that both cooperate in anti-tumour immunity. |
url |
https://doi.org/10.1038/ncomms16073 |
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