N-acetylcysteine addition after vitrification improves oocyte mitochondrial polarization status and the quality of embryos derived from vitrified murine oocytes

N-acetylcysteine addition after vitrification improves oocyte mitochondrial polarization status and the quality of embryos derived from vitrified murine oocytes

Abstract Background Vitrification is the safest method to cryopreserve oocytes, however the process alters mitochondrial function resulting from increased reactive oxygen species (ROS) production. Our aim was to alleviate ROS stress in vitrified mice oocytes using N-acetylcysteine (NAC at 1 mM), to...

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Bibliographic Details
Main Authors: Elvira Matilla, Francisco Eduardo Martín-Cano, Lauro González-Fernández, Francisco Miguel Sánchez-Margallo, Ignacio Santiago Álvarez, Beatriz Macías-García
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Veterinary Research
Subjects:
Mouse
N-acetylcysteine
Oocyte
Vitrification
Online Access:http://link.springer.com/article/10.1186/s12917-018-1743-2

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http://link.springer.com/article/10.1186/s12917-018-1743-2

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