Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial
Abstract Background Delirium has been long considered as a major contributor to cognitive impairments and increased mortality following a critical illness. Pharmacologic and non-pharmacologic strategies are used against delirium in the intensive care unit (ICU), despite these strategies remaining co...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
|
Series: | Trials |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13063-021-05090-2 |
id |
doaj-aa43e32f0d5d4dd9b7eda56ffe9f5b9c |
---|---|
record_format |
Article |
spelling |
doaj-aa43e32f0d5d4dd9b7eda56ffe9f5b9c2021-03-11T12:10:13ZengBMCTrials1745-62152021-03-0122111210.1186/s13063-021-05090-2Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trialAileen C. Naef0Marie-Madlen Jeitziner1Stephan M. Gerber2Béatrice Jenni-Moser3René M. Müri4Stephan M. Jakob5Tobias Nef6Matthias Hänggi7Gerontechnology and Rehabilitation Group, University of BernDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of BernGerontechnology and Rehabilitation Group, University of BernDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of BernDepartment of Neurology, Inselspital, Bern University Hospital, University of BernDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of BernDepartment of Neurology, Inselspital, Bern University Hospital, University of BernDepartment of Intensive Care Medicine, Inselspital, Bern University Hospital, University of BernAbstract Background Delirium has been long considered as a major contributor to cognitive impairments and increased mortality following a critical illness. Pharmacologic and non-pharmacologic strategies are used against delirium in the intensive care unit (ICU), despite these strategies remaining controversial. Previous studies have shown the feasibility of using virtual reality within the ICU setting, and we propose to use this technology to investigate the effect of immersive virtual reality stimulation on the incidence of delirium in the ICU. Moreover, we propose to use motion sensors to determine if patient movement patterns can lead to early prediction of delirium onset. Methods This study is conducted as a randomized clinical trial. A total of 920 critically ill patients in the ICU will participate. The control group will receive standard ICU care, whereas the intervention group will, in addition to the standard ICU care, receive relaxing 360-degree immersive virtual reality content played inside a head-mounted display with noise-cancelling headphones, three times a day. The first 100 patients, regardless of their group, will additionally have their movement patterns recorded using wearable and ambient sensors. Follow-up measurements will take place 6 months after discharge from the ICU. Discussion Delirium is widely present within the ICU setting but lacks validated prevention and treatment strategies. By providing patients with virtual reality stimulation presented inside a head-mounted display and noise-cancelling headphones, participants may be isolated from disturbances on an ICU. It is believed that by doing so, the incidence of delirium will be decrease among these patients. Moreover, identifying movement patterns associated with delirium would allow for early detection and intervention, which may further improve long-term negative outcomes associated with delirium during critical care. Trial registration ClinicalTrials.gov NCT04498585 . Registered on August 3, 2020https://doi.org/10.1186/s13063-021-05090-2DeliriumIntensive careCritical careICUVirtual realityMovement patterns |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Aileen C. Naef Marie-Madlen Jeitziner Stephan M. Gerber Béatrice Jenni-Moser René M. Müri Stephan M. Jakob Tobias Nef Matthias Hänggi |
spellingShingle |
Aileen C. Naef Marie-Madlen Jeitziner Stephan M. Gerber Béatrice Jenni-Moser René M. Müri Stephan M. Jakob Tobias Nef Matthias Hänggi Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial Trials Delirium Intensive care Critical care ICU Virtual reality Movement patterns |
author_facet |
Aileen C. Naef Marie-Madlen Jeitziner Stephan M. Gerber Béatrice Jenni-Moser René M. Müri Stephan M. Jakob Tobias Nef Matthias Hänggi |
author_sort |
Aileen C. Naef |
title |
Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial |
title_short |
Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial |
title_full |
Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial |
title_fullStr |
Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial |
title_full_unstemmed |
Virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial |
title_sort |
virtual reality stimulation to reduce the incidence of delirium in critically ill patients: study protocol for a randomized clinical trial |
publisher |
BMC |
series |
Trials |
issn |
1745-6215 |
publishDate |
2021-03-01 |
description |
Abstract Background Delirium has been long considered as a major contributor to cognitive impairments and increased mortality following a critical illness. Pharmacologic and non-pharmacologic strategies are used against delirium in the intensive care unit (ICU), despite these strategies remaining controversial. Previous studies have shown the feasibility of using virtual reality within the ICU setting, and we propose to use this technology to investigate the effect of immersive virtual reality stimulation on the incidence of delirium in the ICU. Moreover, we propose to use motion sensors to determine if patient movement patterns can lead to early prediction of delirium onset. Methods This study is conducted as a randomized clinical trial. A total of 920 critically ill patients in the ICU will participate. The control group will receive standard ICU care, whereas the intervention group will, in addition to the standard ICU care, receive relaxing 360-degree immersive virtual reality content played inside a head-mounted display with noise-cancelling headphones, three times a day. The first 100 patients, regardless of their group, will additionally have their movement patterns recorded using wearable and ambient sensors. Follow-up measurements will take place 6 months after discharge from the ICU. Discussion Delirium is widely present within the ICU setting but lacks validated prevention and treatment strategies. By providing patients with virtual reality stimulation presented inside a head-mounted display and noise-cancelling headphones, participants may be isolated from disturbances on an ICU. It is believed that by doing so, the incidence of delirium will be decrease among these patients. Moreover, identifying movement patterns associated with delirium would allow for early detection and intervention, which may further improve long-term negative outcomes associated with delirium during critical care. Trial registration ClinicalTrials.gov NCT04498585 . Registered on August 3, 2020 |
topic |
Delirium Intensive care Critical care ICU Virtual reality Movement patterns |
url |
https://doi.org/10.1186/s13063-021-05090-2 |
work_keys_str_mv |
AT aileencnaef virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT mariemadlenjeitziner virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT stephanmgerber virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT beatricejennimoser virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT renemmuri virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT stephanmjakob virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT tobiasnef virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial AT matthiashanggi virtualrealitystimulationtoreducetheincidenceofdeliriumincriticallyillpatientsstudyprotocolforarandomizedclinicaltrial |
_version_ |
1724224710884982784 |