Protocol for assessing and predicting acute respiratory decline in hospitalized patients

Summary: This protocol aids both new and experienced researchers in designing retrospective clinical and translational studies of acute respiratory decline in hospitalized patients. This protocol addresses (1) the basics of respiratory failure and electronic health record research, (2) defining pati...

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Main Authors:	Conor P. Crowley, Louis T. Merriam, Alisa A. Mueller, Tomoyoshi Tamura, Jeremy R. DeGrado, Hibah Haider, Justin D. Salciccioli, Edy Y. Kim
Format:	Article
Language:	English
Published:	Elsevier 2021-06-01
Series:	STAR Protocols
Subjects:	Health Sciences Clinical Protocol Immunology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666166721002525

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spelling	doaj-aa5f5b1233604a70a7f2ce8d4690c84f2021-06-21T04:25:37ZengElsevierSTAR Protocols2666-16672021-06-0122100545Protocol for assessing and predicting acute respiratory decline in hospitalized patientsConor P. Crowley0Louis T. Merriam1Alisa A. Mueller2Tomoyoshi Tamura3Jeremy R. DeGrado4Hibah Haider5Justin D. Salciccioli6Edy Y. Kim7Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA; Corresponding authorDivision of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USADivision of Rheumatology, Brigham and Women’s Hospital, Boston, MA 02115 USA; Harvard Medical School, Boston, MA 02115, USADivision of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USADepartment of Pharmacy, Brigham and Women’s Hospital, Boston, MA 02115 USADivision of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USADivision of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USADivision of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA; Corresponding authorSummary: This protocol aids both new and experienced researchers in designing retrospective clinical and translational studies of acute respiratory decline in hospitalized patients. This protocol addresses (1) the basics of respiratory failure and electronic health record research, (2) defining patient cohorts as “mild, progressive, or severe” instead of “ICU versus non-ICU”, (3) adapting physiological indices, and (4) using biomarker trends. We apply these approaches to inflammatory biomarkers in COVID-19, but this protocol can be applied to any progressive respiratory failure study.For complete details on the use and execution of this protocol, please refer to Mueller et al. (2020).http://www.sciencedirect.com/science/article/pii/S2666166721002525Health SciencesClinical ProtocolImmunology
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Conor P. Crowley Louis T. Merriam Alisa A. Mueller Tomoyoshi Tamura Jeremy R. DeGrado Hibah Haider Justin D. Salciccioli Edy Y. Kim
spellingShingle	Conor P. Crowley Louis T. Merriam Alisa A. Mueller Tomoyoshi Tamura Jeremy R. DeGrado Hibah Haider Justin D. Salciccioli Edy Y. Kim Protocol for assessing and predicting acute respiratory decline in hospitalized patients STAR Protocols Health Sciences Clinical Protocol Immunology
author_facet	Conor P. Crowley Louis T. Merriam Alisa A. Mueller Tomoyoshi Tamura Jeremy R. DeGrado Hibah Haider Justin D. Salciccioli Edy Y. Kim
author_sort	Conor P. Crowley
title	Protocol for assessing and predicting acute respiratory decline in hospitalized patients
title_short	Protocol for assessing and predicting acute respiratory decline in hospitalized patients
title_full	Protocol for assessing and predicting acute respiratory decline in hospitalized patients
title_fullStr	Protocol for assessing and predicting acute respiratory decline in hospitalized patients
title_full_unstemmed	Protocol for assessing and predicting acute respiratory decline in hospitalized patients
title_sort	protocol for assessing and predicting acute respiratory decline in hospitalized patients
publisher	Elsevier
series	STAR Protocols
issn	2666-1667
publishDate	2021-06-01
description	Summary: This protocol aids both new and experienced researchers in designing retrospective clinical and translational studies of acute respiratory decline in hospitalized patients. This protocol addresses (1) the basics of respiratory failure and electronic health record research, (2) defining patient cohorts as “mild, progressive, or severe” instead of “ICU versus non-ICU”, (3) adapting physiological indices, and (4) using biomarker trends. We apply these approaches to inflammatory biomarkers in COVID-19, but this protocol can be applied to any progressive respiratory failure study.For complete details on the use and execution of this protocol, please refer to Mueller et al. (2020).
topic	Health Sciences Clinical Protocol Immunology
url	http://www.sciencedirect.com/science/article/pii/S2666166721002525
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Protocol for assessing and predicting acute respiratory decline in hospitalized patients

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