Cyclosporine A and FK506 as Potent Inhibitors of Streptococcus intermedius Intermedilysin-Induced NFAT-1 Activation
Cyclosporine A (CsA) and tacrolimus (FK506), a member of calcineurin inhibitors, inhibit inflammation process as part of immune response. Nuclear activated T cells subfamily NFAT1 is a trascription factor responsible for the regulation of immune response genes. Streptococcus intermedius, an oral com...
Main Authors: | Heni Susilowati, Hirohiko Okamura, Katsuhiko Hirota, Kaya Yoshida, Atsushi Tabata, Hideaki Nagamune, Tatsuji Haneji, Yoichiro Miyake |
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Format: | Article |
Language: | English |
Published: |
Indonesian Society for Cancer Chemoprevention
2010-06-01
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Series: | ISCC (Indonesian Journal of Cancer Chemoprevention) |
Online Access: | https://ijcc.chemoprev.org/index.php/ijcc/article/view/12 |
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