Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases

Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases

In clinical practice signal hyperintensity in the cortex and/or in the striatum on magnetic resonance (MR) diffusion-weighted images (DWIs) is a marker of sporadic Creutzfeldt–Jakob Disease (sCJD). MR diagnostic accuracy is greater than 90%, but the biophysical mechanisms underpinning the signal ab...

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Bibliographic Details
Main Authors:	Matteo Figini, Daniel C. Alexander, Veronica Redaelli, Fabrizio Fasano, Marina Grisoli, Giuseppe Baselli, Pierluigi Gambetti, Fabrizio Tagliavini, Alberto Bizzi
Format:	Article
Language:	English
Published:	Elsevier 2015-01-01
Series:	NeuroImage: Clinical
Subjects:	Diffusion MRI Biophysical models Creutzfeldt–Jakob disease Prion disease Spongiform degeneration
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213158214001818

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