Redox regulation of RyR-mediated Ca2+ release in muscle and neurons
Changes in the redox state of the intracellular ryanodine receptor/Ca2+ release channels of skeletal and cardiac muscle or brain cortex neurons affect their activity. In particular, agents that oxidize or alkylate free SH residues of the channel protein strongly enhance Ca2+-induced Ca2+ release, wh...
Main Authors: | CECILIA HIDALGO, RICARDO BULL, M. ISABEL BEHRENS, PAULINA DONOSO |
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Format: | Article |
Language: | English |
Published: |
BMC
2004-01-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400007 |
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