Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model.

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model.

To evaluate the ability of the glycolytic enzyme alpha-enolase (ENO1) or its immunodominant peptide (pEP1) to reduce the severity of CIA in DBA/1 mice when injected in a prophylactic way.Mice were treated with mouse ENO1 or pEP1 one day prior to collagen II immunization. Clinical assessment was eval...

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Bibliographic Details
Main Authors: Clément Guillou, Céline Derambure, Manuel Fréret, Mathieu Verdet, Gilles Avenel, Marie-Laure Golinski, Jean-Christophe Sabourin, François Le Loarer, Sahil Adriouch, Olivier Boyer, Thierry Lequerré, Olivier Vittecoq
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4547710?pdf=render

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http://europepmc.org/articles/PMC4547710?pdf=render

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