To Infection and Beyond: The Multi-Pronged Anti-Cancer Mechanisms of Oncolytic Viruses

Over the past 1–2 decades we have witnessed a resurgence of efforts to therapeutically exploit the attributes of lytic viruses to infect and kill tumor cells while sparing normal cells. We now appreciate that the utility of viruses for treating cancer extends far beyond lytic cell death. Viruses are...

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Bibliographic Details
Main Authors: Kevin A. Cassady, Kellie B. Haworth, Josh Jackson, James M. Markert, Timothy P. Cripe
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/2/43