Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China
Abstract Background Positive associations between ambient PM2.5 and cardiorespiratory disease have been well demonstrated during the past decade. However, few studies have examined the adverse effects of PM2.5 based on an entire population of a megalopolis. In addition, most studies in China have us...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
|
Series: | Respiratory Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12931-021-01731-x |
id |
doaj-aab8c7f463664a0fa804075fb9e16f5b |
---|---|
record_format |
Article |
spelling |
doaj-aab8c7f463664a0fa804075fb9e16f5b2021-05-02T11:17:09ZengBMCRespiratory Research1465-993X2021-04-0122111110.1186/s12931-021-01731-xEffect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, ChinaZhan Ren0Xingyuan Liu1Tianyu Liu2Dieyi Chen3Kuizhuang Jiao4Xiaodie Wang5Jingdong Suo6Haomin Yang7Jingling Liao8Lu Ma9Wuhan University School of Health SciencesWuhan Information Center of Health and Family PlanningWuhan University School of Health SciencesDepartment of Biostatistics, Yale UniversityWuhan University School of Health SciencesWuhan University School of Health SciencesWuhan University School of Health SciencesWuhan University School of Health SciencesDepartment of Nutrition and Food Hygiene, School of Public Health, Medical College, Wuhan University of Science and TechnologyWuhan University School of Health SciencesAbstract Background Positive associations between ambient PM2.5 and cardiorespiratory disease have been well demonstrated during the past decade. However, few studies have examined the adverse effects of PM2.5 based on an entire population of a megalopolis. In addition, most studies in China have used averaged data, which results in variations between monitoring and personal exposure values, creating an inherent and unavoidable type of measurement error. Methods This study was conducted in Wuhan, a megacity in central China with about 10.9 million people. Daily hospital admission records, from October 2016 to December 2018, were obtained from the Wuhan Information center of Health and Family Planning, which administrates all hospitals in Wuhan. Daily air pollution concentrations and weather variables in Wuhan during the study period were collected. We developed a land use regression model (LUR) to assess individual PM2.5 exposure. Time-stratified case-crossover design and conditional logistic regression models were adopted to estimate cardiorespiratory hospitalization risks associated with short-term exposure to PM2.5. We also conducted stratification analyses by age, sex, and season. Results A total of 2,806,115 hospital admissions records were collected during the study period, from which we identified 332,090 cardiovascular disease admissions and 159,365 respiratory disease admissions. Short-term exposure to PM2.5 was associated with an increased risk of a cardiorespiratory hospital admission. A 10 μg/m3 increase in PM2.5 (lag0–2 days) was associated with an increase in hospital admissions of 1.23% (95% CI 1.01–1.45%) and 1.95% (95% CI 1.63–2.27%) for cardiovascular and respiratory diseases, respectively. The elderly were at higher PM-induced risk. The associations appeared to be more evident in the cold season than in the warm season. Conclusions This study contributes evidence of short-term effects of PM2.5 on cardiorespiratory hospital admissions, which may be helpful for air pollution control and disease prevention in Wuhan.https://doi.org/10.1186/s12931-021-01731-xAir pollutionParticulate matterSpatial epidemiologyCase-crossover study |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zhan Ren Xingyuan Liu Tianyu Liu Dieyi Chen Kuizhuang Jiao Xiaodie Wang Jingdong Suo Haomin Yang Jingling Liao Lu Ma |
spellingShingle |
Zhan Ren Xingyuan Liu Tianyu Liu Dieyi Chen Kuizhuang Jiao Xiaodie Wang Jingdong Suo Haomin Yang Jingling Liao Lu Ma Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China Respiratory Research Air pollution Particulate matter Spatial epidemiology Case-crossover study |
author_facet |
Zhan Ren Xingyuan Liu Tianyu Liu Dieyi Chen Kuizhuang Jiao Xiaodie Wang Jingdong Suo Haomin Yang Jingling Liao Lu Ma |
author_sort |
Zhan Ren |
title |
Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China |
title_short |
Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China |
title_full |
Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China |
title_fullStr |
Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China |
title_full_unstemmed |
Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China |
title_sort |
effect of ambient fine particulates (pm2.5) on hospital admissions for respiratory and cardiovascular diseases in wuhan, china |
publisher |
BMC |
series |
Respiratory Research |
issn |
1465-993X |
publishDate |
2021-04-01 |
description |
Abstract Background Positive associations between ambient PM2.5 and cardiorespiratory disease have been well demonstrated during the past decade. However, few studies have examined the adverse effects of PM2.5 based on an entire population of a megalopolis. In addition, most studies in China have used averaged data, which results in variations between monitoring and personal exposure values, creating an inherent and unavoidable type of measurement error. Methods This study was conducted in Wuhan, a megacity in central China with about 10.9 million people. Daily hospital admission records, from October 2016 to December 2018, were obtained from the Wuhan Information center of Health and Family Planning, which administrates all hospitals in Wuhan. Daily air pollution concentrations and weather variables in Wuhan during the study period were collected. We developed a land use regression model (LUR) to assess individual PM2.5 exposure. Time-stratified case-crossover design and conditional logistic regression models were adopted to estimate cardiorespiratory hospitalization risks associated with short-term exposure to PM2.5. We also conducted stratification analyses by age, sex, and season. Results A total of 2,806,115 hospital admissions records were collected during the study period, from which we identified 332,090 cardiovascular disease admissions and 159,365 respiratory disease admissions. Short-term exposure to PM2.5 was associated with an increased risk of a cardiorespiratory hospital admission. A 10 μg/m3 increase in PM2.5 (lag0–2 days) was associated with an increase in hospital admissions of 1.23% (95% CI 1.01–1.45%) and 1.95% (95% CI 1.63–2.27%) for cardiovascular and respiratory diseases, respectively. The elderly were at higher PM-induced risk. The associations appeared to be more evident in the cold season than in the warm season. Conclusions This study contributes evidence of short-term effects of PM2.5 on cardiorespiratory hospital admissions, which may be helpful for air pollution control and disease prevention in Wuhan. |
topic |
Air pollution Particulate matter Spatial epidemiology Case-crossover study |
url |
https://doi.org/10.1186/s12931-021-01731-x |
work_keys_str_mv |
AT zhanren effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT xingyuanliu effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT tianyuliu effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT dieyichen effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT kuizhuangjiao effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT xiaodiewang effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT jingdongsuo effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT haominyang effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT jinglingliao effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina AT luma effectofambientfineparticulatespm25onhospitaladmissionsforrespiratoryandcardiovasculardiseasesinwuhanchina |
_version_ |
1721492433462624256 |