Insights Into Protein S-Palmitoylation in Synaptic Plasticity and Neurological Disorders: Potential and Limitations of Methods for Detection and Analysis

Insights Into Protein S-Palmitoylation in Synaptic Plasticity and Neurological Disorders: Potential and Limitations of Methods for Detection and Analysis

S-palmitoylation (S-PALM) is a lipid modification that involves the linkage of a fatty acid chain to cysteine residues of the substrate protein. This common posttranslational modification (PTM) is unique among other lipid modifications because of its reversibility. Hence, like phosphorylation or ubi...

Full description

Bibliographic Details
Main Authors: Monika Zaręba-Kozioł, Izabela Figiel, Anna Bartkowiak-Kaczmarek, Jakub Włodarczyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
S-palmitoylation
synapse
neurodegenerative diseases
metabolic labeling
biochemical methods
synaptic plasticity
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00175/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00175/full

Similar Items