Imaging and Quantification of mRNA Molecules at Single-Cell Resolution in the Human Fungal Pathogen Candida albicans

Tools to visualize and quantify transcripts at single-cell resolution have enabled the dissection of spatiotemporal patterns of gene expression in animal cells and tissues. Yet the accurate quantification of transcripts at single-cell resolution remains challenging for the much smaller microbial ce...

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Bibliographic Details
Main Authors: Sergio D. Moreno-Velásquez, J. Christian Pérez
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00411-21
Description
Summary:Tools to visualize and quantify transcripts at single-cell resolution have enabled the dissection of spatiotemporal patterns of gene expression in animal cells and tissues. Yet the accurate quantification of transcripts at single-cell resolution remains challenging for the much smaller microbial cells.
ISSN:2379-5042