The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation

Atrial fibrillation (AF) is the most common persistent arrhythmia, but the mechanism of AF has not been fully elucidated, and existing approaches to diagnosis and treatment face limitations. Recently, exosomes have attracted considerable interest in AF research due to their high stability, specifici...

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Main Authors:	Shengyuan Huang, Yating Deng, Jiaqi Xu, Jiachen Liu, Liming Liu, Chengming Fan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	non-coding RNA exosomes atrial fibrillation biomarkers mechanism treatment
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2021.712828/full

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spelling	doaj-aaf385cbddc043eca0985e0361415c4a2021-07-28T04:59:44ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-07-01810.3389/fcvm.2021.712828712828The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial FibrillationShengyuan Huang0Yating Deng1Jiaqi Xu2Jiachen Liu3Liming Liu4Chengming Fan5Department of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaXiangya Medical College of Central South University, Changsha, ChinaDepartment of Spine Surgery and Orthopaedics, Xiangya Hospital, Central South University, Changsha, ChinaXiangya Medical College of Central South University, Changsha, ChinaDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, ChinaAtrial fibrillation (AF) is the most common persistent arrhythmia, but the mechanism of AF has not been fully elucidated, and existing approaches to diagnosis and treatment face limitations. Recently, exosomes have attracted considerable interest in AF research due to their high stability, specificity and cell-targeting ability. The aim of this review is to summarize recent literature, analyze the advantages and limitations of exosomes, and to provide new ideas for their use in understanding the mechanism and improving the diagnosis and treatment of AF.https://www.frontiersin.org/articles/10.3389/fcvm.2021.712828/fullnon-coding RNAexosomesatrial fibrillationbiomarkersmechanismtreatment
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Shengyuan Huang Yating Deng Jiaqi Xu Jiachen Liu Liming Liu Chengming Fan
spellingShingle	Shengyuan Huang Yating Deng Jiaqi Xu Jiachen Liu Liming Liu Chengming Fan The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation Frontiers in Cardiovascular Medicine non-coding RNA exosomes atrial fibrillation biomarkers mechanism treatment
author_facet	Shengyuan Huang Yating Deng Jiaqi Xu Jiachen Liu Liming Liu Chengming Fan
author_sort	Shengyuan Huang
title	The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation
title_short	The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation
title_full	The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation
title_fullStr	The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation
title_full_unstemmed	The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation
title_sort	role of exosomes and their cargos in the mechanism, diagnosis, and treatment of atrial fibrillation
publisher	Frontiers Media S.A.
series	Frontiers in Cardiovascular Medicine
issn	2297-055X
publishDate	2021-07-01
description	Atrial fibrillation (AF) is the most common persistent arrhythmia, but the mechanism of AF has not been fully elucidated, and existing approaches to diagnosis and treatment face limitations. Recently, exosomes have attracted considerable interest in AF research due to their high stability, specificity and cell-targeting ability. The aim of this review is to summarize recent literature, analyze the advantages and limitations of exosomes, and to provide new ideas for their use in understanding the mechanism and improving the diagnosis and treatment of AF.
topic	non-coding RNA exosomes atrial fibrillation biomarkers mechanism treatment
url	https://www.frontiersin.org/articles/10.3389/fcvm.2021.712828/full
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The Role of Exosomes and Their Cargos in the Mechanism, Diagnosis, and Treatment of Atrial Fibrillation

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