N-myc Downstream Regulated Gene 1 (NDRG1) Is Fused to ERG in Prostate Cancer

N-myc Downstream Regulated Gene 1 (NDRG1) Is Fused to ERG in Prostate Cancer

A step toward the molecular classification of prostate cancer was the discovery of recurrent erythroblast transformation. specific rearrangements, most commonly fusing the androgen-regulated TMPRSS2 promoter to ERG. The TMPRSS2-ERG fusion is observed in around 90% of tumors that overexpress the onc...

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Bibliographic Details
Main Authors: Dorothee Pflueger, David S. Rickman, Andrea Sboner, Sven Perner, Christopher J. LaFargue, Maria A. Svensson, Benjamin J. Moss, Naoki Kitabayashi, Yihang Pan, Alexandre de la Taille, Rainer Kuefer, Ashutosh K. Tewari, Francesca Demichelis, Mark S. Chee, Mark B. Gerstein, Mark A. Rubin
Format: Article
Language:English
Published: Elsevier 2009-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860980136X

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