RNA Trans-Splicing Modulation via Antisense Molecule Interference

RNA Trans-Splicing Modulation via Antisense Molecule Interference

In recent years, RNA trans-splicing has emerged as a suitable RNA editing tool for the specific replacement of mutated gene regions at the pre-mRNA level. Although the technology has been successfully applied for the restoration of protein function in various genetic diseases, a higher trans-splicin...

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Bibliographic Details
Main Authors: Bernadette Liemberger, Josefina Piñón Hofbauer, Verena Wally, Claudia Arzt, Stefan Hainzl, Thomas Kocher, Eva M. Murauer, Johann W. Bauer, Julia Reichelt, Ulrich Koller
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
RNA trans-splicing
RNA therapy
fluorescence-based screening system
antisense molecules
epidermolysis bullosa
KRT14
Online Access:http://www.mdpi.com/1422-0067/19/3/762

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