Patient-Reported Disease Severity and Quality of Life Among Arabic Psoriatic Patients: A Cross-Sectional Survey

• Main Author: Soliman M
• Format: Article
• Language: English
• Published: Dove Medical Press 2020-08-01
• Series: Clinical, Cosmetic and Investigational Dermatology
• Subjects: self-assessed simplified psoriasis index; psoriasis; quality of life; cross-sectional; patient-reported measures
• Online Access: https://www.dovepress.com/patient-reported-disease-severity-and-quality-of-life-among-arabic-pso-peer-reviewed-article-CCID

Moetaza Soliman Department of Pharmacy Practice, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptCorrespondence: Moetaza SolimanDepartment of Pharmacy Practice, Faculty of Pharmacy, Mansoura University, ElGomhoria Street, Mansoura, ElDakahlia, EgyptTel [phone]Email [e-mail]: Patient-reported measures are of importance in chronic dermatological conditions where psychosocial consequences and quality of life impairment are common. The current study aimed to evaluate patient-reported disease severity and quality of life in Arabic patients with psoriasis.Patients and Methods: Arabic psoriatic patients were invited to complete an online survey that collected patients’ demographics, self-assessed Simplified Psoriasis Index (saSPI) and the Dermatology Life Quality Index (DLQI). Disease severity and quality of life were compared in relation to patients’ demographics. Correlation between patient-reported measures was calculated using Spearman’s rank correlation test.Results: A total of 221 patients with psoriasis, from 12 Arabic-speaking countries, participated in the study. The mean (95% CIs) saSPI-severity score was 10.9 (9.6– 12.2). Female patients reported higher saSPI-psychosocial impact scores compared to males (P=0.04) while patients with longer disease duration reported higher saSPI-past history and interventions scores (P=0.0001). The mean (95% CIs) DLQI score was 11.2 (10.2– 12.1). Patients with severe disease reported significantly higher DLQI scores [18.5 (10.5– 2)] (P=0.0001). DLQI was strongly correlated with saSPI-psychosocial impact score (rho= 0.63).Conclusion: Arabic psoriatic patients participating in this study showed mild to moderate disease severity which had a very large impact on patients’ quality of life. Higher disease severity was associated with more impaired quality of life.Keywords: self-assessed Simplified Psoriasis Index, psoriasis, quality of life, cross-sectional, patient-reported measures