Antimicrobial peptide GH12 targets Streptococcus mutans to arrest caries development in rats

Antimicrobial peptide GH12 targets Streptococcus mutans to arrest caries development in rats

Background:Targeting Streptococcus mutans, the principle cariogenic bacterium, could prove to be an effective means of preventing dental caries. A de novo designed antimicrobial peptide, GH12, has shown bactericidal effects on S. mutans and inhibitory effects on virulence and regulatory systems of S...

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Bibliographic Details
Main Authors: Yufei Wang, Yuhao Zeng, Yuanjing Wang, Haoran Li, Sihan Yu, Wentao Jiang, Yingxue Li, Linglin Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Oral Microbiology
Subjects:
dental caries
antimicrobial peptides
rats
streptococcus mutans
antimicrobial agents
biofilms
Online Access:http://dx.doi.org/10.1080/20002297.2018.1549921

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