Three Distinct Patterns of Histone H3Y41 Phosphorylation Mark Active Genes

Three Distinct Patterns of Histone H3Y41 Phosphorylation Mark Active Genes

The JAK2 tyrosine kinase is a critical mediator of cytokine-induced signaling. It plays a role in the nucleus, where it regulates transcription by phosphorylating histone H3 at tyrosine 41 (H3Y41ph). We used chromatin immunoprecipitation coupled to massively parallel DNA sequencing (ChIP-seq) to de...

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Bibliographic Details
Main Authors: Mark A. Dawson, Samuel D. Foster, Andrew J. Bannister, Samuel C. Robson, Rebecca Hannah, Xiaonan Wang, Blerta Xhemalce, Andrew D. Wood, Anthony R. Green, Berthold Göttgens, Tony Kouzarides
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712002410

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http://www.sciencedirect.com/science/article/pii/S2211124712002410

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