Thyrotoxicosis with osteomalacia and proximal myopathy.

• Main Authors: Goswami R, Shah P, Ammini A
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 1993-04-01
• Series: Journal of Postgraduate Medicine
• Subjects: Adult; Case Report; Female; Human; Muscular Diseases; etiology; Osteomalacia; complications; Thyrotoxicosis
• Online Access: http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1993;volume=39;issue=2;spage=89;epage=90;aulast=Goswami

A 36 year old lady, presented with symptoms of proximal myopathy was found to have a history of thyrotoxicosis for which she had taken carbimazole irregularly for 1-1/2 years. On admission, clinical signs of thyrotoxicosis were detected and confirmed by estimating serum T3 and T4. Neurological examination revealed generalised wasting, loss of power in the proximal muscles with a myopathy confirmed on EMG. Serum calcium, phosphorous levels, and a 24 hour urine calcium excretion were low. Alkaline phosphatase levels were high. A diagnosis of thyrotoxicosis with osteomalacia was made. The patient improved within 3 weeks of starting carbimazole and vitamin D.