Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters
Passive and composite sampling in combination with in vitro bioassays and identification and quantification of individual chemicals were applied to characterize pollution by compounds with several specific modes of action in urban area in the basin of two rivers, with 400,000 inhabitants and a varie...
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doaj-ab6c3d1b29564856bf15a7185c16169c2020-11-25T01:38:31ZengElsevierEnvironment International0160-41202013-09-0159372383Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface watersV. Jálová0B. Jarošová1L. Bláha2J.P. Giesy3T. Ocelka4R. Grabic5J. Jurčíková6B. Vrana7K. Hilscherová8Research Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, Kamenice 753/5, 625 00, Brno, Czech RepublicResearch Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, Kamenice 753/5, 625 00, Brno, Czech RepublicResearch Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, Kamenice 753/5, 625 00, Brno, Czech RepublicDept. of Biomedical Veterinary Sciences and Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing, 210046, PR China; Department of Zoology, Center for Integrative Toxicology, Michigan State University, East Lansing, MI, USA; School of Biological Sciences, University of Hong Kong, Hong Kong, China; Department of Biology and Chemistry, State Key Laboratory for Marine Pollution, City University of Hong Kong, Hong Kong, ChinaInstitute of Public Health Ostrava, National Reference Laboratory for POPs, Ostrava, Czech RepublicUniversity of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Zatisi 728/II, Vodnany, 389 25 Czech RepublicInstitute of Public Health Ostrava, National Reference Laboratory for POPs, Ostrava, Czech RepublicResearch Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, Kamenice 753/5, 625 00, Brno, Czech RepublicResearch Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, Kamenice 753/5, 625 00, Brno, Czech Republic; Corresponding author. Tel.: +420 54949 3256; fax: +420 54949 2840.Passive and composite sampling in combination with in vitro bioassays and identification and quantification of individual chemicals were applied to characterize pollution by compounds with several specific modes of action in urban area in the basin of two rivers, with 400,000 inhabitants and a variety of industrial activities. Two types of passive samplers, semipermeable membrane devices (SPMD) for hydrophobic contaminants and polar organic chemical integrative samplers (POCIS) for polar compounds such as pesticides and pharmaceuticals, were used to sample wastewater treatment plant (WWTP) influent and effluent as well as rivers upstream and downstream of the urban complex and the WWTP. Compounds with endocrine disruptive potency were detected in river water and WWTP influent and effluent. Year-round, monthly assessment of waste waters by bioassays documented estrogenic, androgenic and dioxin-like potency as well as cytotoxicity in influent waters of the WWTP and allowed characterization of seasonal variability of these biological potentials in waste waters. The WWTP effectively removed cytotoxic compounds, xenoestrogens and xenoandrogens. There was significant variability in treatment efficiency of dioxin-like potency. The study indicates that the WWTP, despite its up-to-date technology, can contribute endocrine disrupting compounds to the river. Riverine samples exhibited dioxin-like, antiestrogenic and antiandrogenic potencies. The study design enabled characterization of effects of the urban complex and the WWTP on the river. Concentrations of PAHs and contaminants and specific biological potencies sampled by POCIS decreased as a function of distance from the city. Keywords: Estrogenic, Androgenic, Cytotoxicity, Bioassay in vitro, Passive sampling, Dioxin-likehttp://www.sciencedirect.com/science/article/pii/S0160412013001426 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
V. Jálová B. Jarošová L. Bláha J.P. Giesy T. Ocelka R. Grabic J. Jurčíková B. Vrana K. Hilscherová |
spellingShingle |
V. Jálová B. Jarošová L. Bláha J.P. Giesy T. Ocelka R. Grabic J. Jurčíková B. Vrana K. Hilscherová Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters Environment International |
author_facet |
V. Jálová B. Jarošová L. Bláha J.P. Giesy T. Ocelka R. Grabic J. Jurčíková B. Vrana K. Hilscherová |
author_sort |
V. Jálová |
title |
Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters |
title_short |
Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters |
title_full |
Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters |
title_fullStr |
Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters |
title_full_unstemmed |
Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters |
title_sort |
estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters |
publisher |
Elsevier |
series |
Environment International |
issn |
0160-4120 |
publishDate |
2013-09-01 |
description |
Passive and composite sampling in combination with in vitro bioassays and identification and quantification of individual chemicals were applied to characterize pollution by compounds with several specific modes of action in urban area in the basin of two rivers, with 400,000 inhabitants and a variety of industrial activities. Two types of passive samplers, semipermeable membrane devices (SPMD) for hydrophobic contaminants and polar organic chemical integrative samplers (POCIS) for polar compounds such as pesticides and pharmaceuticals, were used to sample wastewater treatment plant (WWTP) influent and effluent as well as rivers upstream and downstream of the urban complex and the WWTP. Compounds with endocrine disruptive potency were detected in river water and WWTP influent and effluent. Year-round, monthly assessment of waste waters by bioassays documented estrogenic, androgenic and dioxin-like potency as well as cytotoxicity in influent waters of the WWTP and allowed characterization of seasonal variability of these biological potentials in waste waters. The WWTP effectively removed cytotoxic compounds, xenoestrogens and xenoandrogens. There was significant variability in treatment efficiency of dioxin-like potency. The study indicates that the WWTP, despite its up-to-date technology, can contribute endocrine disrupting compounds to the river. Riverine samples exhibited dioxin-like, antiestrogenic and antiandrogenic potencies. The study design enabled characterization of effects of the urban complex and the WWTP on the river. Concentrations of PAHs and contaminants and specific biological potencies sampled by POCIS decreased as a function of distance from the city. Keywords: Estrogenic, Androgenic, Cytotoxicity, Bioassay in vitro, Passive sampling, Dioxin-like |
url |
http://www.sciencedirect.com/science/article/pii/S0160412013001426 |
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