HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis.
The phylogeographic population structure of Mycobacterium tuberculosis suggests local adaptation to sympatric human populations. We hypothesized that HIV infection, which induces immunodeficiency, will alter the sympatric relationship between M. tuberculosis and its human host. To test this hypothes...
Main Authors: | Lukas Fenner, Matthias Egger, Thomas Bodmer, Hansjakob Furrer, Marie Ballif, Manuel Battegay, Peter Helbling, Jan Fehr, Thomas Gsponer, Hans L Rieder, Marcel Zwahlen, Matthias Hoffmann, Enos Bernasconi, Matthias Cavassini, Alexandra Calmy, Marisa Dolina, Reno Frei, Jean-Paul Janssens, Sonia Borrell, David Stucki, Jacques Schrenzel, Erik C Böttger, Sebastien Gagneux, Swiss HIV Cohort and Molecular Epidemiology of Tuberculosis Study Groups |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS Genetics |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23505379/?tool=EBI |
Similar Items
-
Tuberculosis in HIV-negative and HIV-infected patients in a low-incidence country: clinical characteristics and treatment outcomes.
by: Lukas Fenner, et al.
Published: (2012-01-01) -
Impact of previous virological treatment failures and adherence on the outcome of antiretroviral therapy in 2007.
by: Marie Ballif, et al.
Published: (2009-01-01) -
Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis
by: Teja Turk, et al.
Published: (2017-09-01) -
Improved sensitivity of an interferon-gamma release assay (T-SPOT.TB™) in combination with tuberculin skin test for the diagnosis of latent tuberculosis in the presence of HIV co-Infection
by: Elzi Luigia, et al.
Published: (2011-11-01) -
Rilpivirine use in the Swiss HIV cohort study: a prospective cohort study
by: Delphine Sculier, et al.
Published: (2017-07-01)