More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells

More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells

<p>Abstract</p> <p>Background</p> <p>Brain-derived neurotrophic factor (BDNF) and its receptor Tropomysin-related kinase B (TrkB) are commonly up-regulated in a variety of human tumors. However, the roles of BDNF/TrkB in hepatocellular carcinoma (HCC) have been poorly i...

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Bibliographic Details
Main Authors: Liang Jian, Zhu Lei, Sun Wenyu, Zhang Hongbin, Hou Xuezhong, Guo Dawei, Jiang Xiaofeng
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/30/1/97

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