Somatic Mutation in Immunoglobulin Gene Variable Region in Patients with Chronic Lymphocytic Leukemia and Prognostic Impact

Somatic Mutation in Immunoglobulin Gene Variable Region in Patients with Chronic Lymphocytic Leukemia and Prognostic Impact

Chronic lymphocyte leukemia (CLL) is the most common leukemia in elderly individuals that is accompanied by the presence of CD5/CD19/CD20/CD23 positive, FMC7 negative and reduced levels of surface membrane Immunoglobuline (IgM & IgD), CD79b on B lymphocytes in the blood, bone marrow and lymph n...

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Bibliographic Details
Main Authors: Mehrnoosh Pashaei, Mahdieh Shokrollahi, Parviz Kokhaei
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2017-02-01
Series:Basic & Clinical Cancer Research
Subjects:
CLL
mutation IgVH status
prognosis factor
overall survival
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/218

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