RESULTS OF AN OPEN, MONOCENTERED NON-RANDOMISED, WITHOUT CONTROL GROUP, OBSERVATIONAL QUALITY OF LIFE EVALUATION STUDY IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS TREATED WITH ETARNECEPT IN COMBINATION WITH METHOTREXATE

• Main Authors: Е.I. Alexeeva, T.М. Bzarova, N.A. Tsurikova, R.V. Denisova
• Format: Article
• Language: English
• Published: "Paediatrician" Publishers LLC 2011-01-01
• Series: Voprosy Sovremennoj Pediatrii
• Subjects: juvenile idiopathic arthritis; etarnecept; methotrexate; quality of life; efficacy; safety
• Online Access: http://vsp.spr-journal.ru:80/jour/article/view/771
• ISSN: 1682-5527; 1682-5535

<p><em>Study objective — to evaluate etarnecept influence on quality of life of idiopathic juvenile arthritis patients’ quality of life. 25 patients with poly- and oligoarthritides aged 8 (6; 11) years. Before etarnecept use quality of life of all patients was significantly lower that that of healthy children judging upon children’s own opinion and that of their parents. No longer that after 1 month since the beginning of etarnecept treatment 92% of patients claimed significant increase in their quality of life (according to patients’ opinion, total score increase from 53 to 59, from 49 to 60, according to parents (p &lt; 0,001). After 12 months of treatment 68 % of patients had quality of life similar to the one of healthy children.</em><strong><em></em></strong></p><p><strong><em>Key words: juvenile idiopathic arthritis, etarnecept, methotrexate, quality of life, efficacy, safety.</em></strong><strong> </strong><br /><em><span style="text-decoration: underline;">(<em><span><em><em><em>Voprosy sovremennoi pediatrii — </em></em></em></span></em></span></em><em><span style="text-decoration: underline;">Current Pediatrics. — 2011; 10 (6): 26–34.)</span></em></p>