SkewIT: The Skew Index Test for large-scale GC Skew analysis of bacterial genomes.
GC skew is a phenomenon observed in many bacterial genomes, wherein the two replication strands of the same chromosome contain different proportions of guanine and cytosine nucleotides. Here we demonstrate that this phenomenon, which was first discovered in the mid-1990s, can be used today as an ana...
Main Authors: | Jennifer Lu, Steven L Salzberg |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-12-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1008439 |
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