Hemophilia prophylaxis adherence and bleeding using a tailored, frequency‐escalated approach: The Canadian Hemophilia Primary Prophylaxis Study

Hemophilia prophylaxis adherence and bleeding using a tailored, frequency‐escalated approach: The Canadian Hemophilia Primary Prophylaxis Study

Abstract Background Standard of care for persons with severe hemophilia A includes regular replacement of factor VIII (FVIII). Prophylaxis regimens using standard half‐life (SHL) FVIII concentrates, while effective, are costly and require frequent intravenous infusions. Aim This study evaluated the...

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Bibliographic Details
Main Authors: Saunya Dover, Victor S. Blanchette, Darius Wrathall, Eleanor Pullenayegum, Daniel Kazandjian, Byron Song, Sue Ann Hawes, Stéphanie Cloutier, Geroges E. Rivard, Robert J. Klaassen, Elizabeth Paradis, Nicole Laferriere, Ann Marie Stain, Anthony K. Chan, Sara J. Israels, Roona Sinha, MacGregor Steele, John K. M. Wu, Brian M. Feldman
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
bleeding
factor VIII
hemophilia A
prophylaxis
treatment adherence and compliance
Online Access:https://doi.org/10.1002/rth2.12301

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