Poly(I:C) Potentiates T Cell Immunity to a Dendritic Cell Targeted HIV-Multiepitope Vaccine

Poly(I:C) Potentiates T Cell Immunity to a Dendritic Cell Targeted HIV-Multiepitope Vaccine

Cellular immune responses are implicated in resistance to HIV and have been considered for the development of an effective vaccine. Despite their safety profile, subunit vaccines need to be delivered combined with an adjuvant. In the last years, in vivo antigen targeting to dendritic cells (DCs) usi...

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Bibliographic Details
Main Authors: Juliana de Souza Apostólico, Victória Alves Santos Lunardelli, Marcio Massao Yamamoto, Edecio Cunha-Neto, Silvia Beatriz Boscardin, Daniela Santoro Rosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
HIV
multiepitope vaccine
dendritic cell targeting
DEC205
adjuvants
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00843/full

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