Rhoptry and Dense Granule Secreted Effectors Regulate CD8+ T Cell Recognition of Toxoplasma gondii Infected Host Cells
Toxoplasma gondii secretes rhoptry (ROP) and dense granule (GRA) effector proteins to evade host immune clearance mediated by interferon gamma (IFN-γ), immunity-related GTPase (IRG) effectors, and CD8+ T cells. Here, we investigated the role of parasite-secreted effectors in regulating host access t...
Main Authors: | Leah M. Rommereim, Barbara A. Fox, Kiah L. Butler, Viviana Cantillana, Gregory A. Taylor, David J. Bzik |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-09-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2019.02104/full |
Similar Items
-
A Member of the Ferlin Calcium Sensor Family Is Essential for Toxoplasma gondii Rhoptry Secretion
by: Bradley I. Coleman, et al.
Published: (2018-10-01) -
Ferlins and TgDOC2 in <i>Toxoplasma</i> Microneme, Rhoptry and Dense Granule Secretion
by: Daniel N. A. Tagoe, et al.
Published: (2021-03-01) -
Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18
by: Diego Molina, et al.
Published: (2018-11-01) -
DNA vaccination with a gene encoding Toxoplasma gondii Rhoptry Protein 17 induces partial protective immunity against lethal challenge in mice
by: Wang Hai-Long, et al.
Published: (2016-01-01) -
Sequence Variation in Rhoptry Neck Protein 10 Gene among Toxoplasma gondii Isolates from Different Hosts and Geographical Locations
by: Yu ZHAO, et al.
Published: (2017-09-01)